Recent advances in isocyanide-based multicomponent chemistryDömling, A., 1-Jun-2002, In : Current Opinion in Chemical Biology. 6, 3, p. 306-313 8 p.
Research output: Contribution to journal › Book/Film/Article review › Professional
Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of diverse and complex compounds on the one hand and small and 'drug-like' heterocycles on the other hand. No other single synthesis technology enables chemists to search such large chemical spaces as provided by MCRs. MCRs that involve isocyanides are by far the most versatile reactions in terms of scaffolds and number of accessible compounds.
|Number of pages||8|
|Journal||Current Opinion in Chemical Biology|
|Publication status||Published - 1-Jun-2002|
- heterocyclic amine, isocyanic acid derivative, nonhuman, review, synthesis