Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression

Brown, N. J. L. & Nickerson, C. A. Mar-2016 In : Personality and Individual Differences. 91, p. 133-137 5 p.

Research output: Contribution to journalReview article

A recent study by Vedhara et al. appearing in Psychoneuroendocrinology (2015,52, 72-82) concluded that the personality traits of conscientiousness and extraversion were associated with the decreased and increased expression of pro-inflammatory genes, respectively. A reanalysis of the data from this study indicates that these results are fragile and ambiguous, and depend on (a) the inclusion or exclusion of two study participants missing values for one of the control variables and (b) the accumulation of statistical suppression effects in the regression analyses. (C) 2015 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalPersonality and Individual Differences
StatePublished - Mar-2016


  • Gene expression, Immunity, Personality, Pro-inflammatory, SITUATIONS

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