Publication

Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI

Heus, A., Arends, S., Van Nimwegen, J. F., Stei, A. J., Nossent, G. D. & Bootsma, H., 25-Sep-2019, In : Scandinavian Journal of Rheumatology. 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Heus, A., Arends, S., Van Nimwegen, J. F., Stei, A. J., Nossent, G. D., & Bootsma, H. (2019). Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI. Scandinavian Journal of Rheumatology. https://doi.org/10.1080/03009742.2019.1634221

Author

Heus, A. ; Arends, S. ; Van Nimwegen, J. F. ; Stei, A. J. ; Nossent, G. D. ; Bootsma, H. / Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI. In: Scandinavian Journal of Rheumatology. 2019.

Harvard

Heus, A, Arends, S, Van Nimwegen, JF, Stei, AJ, Nossent, GD & Bootsma, H 2019, 'Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI', Scandinavian Journal of Rheumatology. https://doi.org/10.1080/03009742.2019.1634221

Standard

Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI. / Heus, A.; Arends, S.; Van Nimwegen, J. F.; Stei, A. J.; Nossent, G. D.; Bootsma, H.

In: Scandinavian Journal of Rheumatology, 25.09.2019.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Heus A, Arends S, Van Nimwegen JF, Stei AJ, Nossent GD, Bootsma H. Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI. Scandinavian Journal of Rheumatology. 2019 Sep 25. https://doi.org/10.1080/03009742.2019.1634221


BibTeX

@article{703b75e7559f492cb3b34b5f6fe80e63,
title = "Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI",
abstract = "Objective: Systemic features influence disease prognosis and choice of treatment in primary Sjogren's syndrome (pSS). Our aim was to investigate the prevalence of pulmonary involvement in pSS patients and to classify patients according to the pulmonary domain of the EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI). Methods: This retrospective cohort study included consecutive pSS patients, fulfilling American-European Consensus Group/American College of Rheumatology classification criteria, who visited the Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, in 2015. Data on pulmonary complaints and pulmonary tests were obtained from electronic patient records. Pulmonary involvement was recorded if therapy was needed or follow-up was recommended, and when it was possibly or assumed to be related to pSS instead of coincidental factors. Results: Of the 262 included pSS patients, 88 (34{\%}) had pulmonary complaints, mostly cough or dyspnoea on exertion. Pulmonary diagnostics were performed in 225 patients (86{\%}). Pulmonary involvement was present and assumed to be related to pSS in 25 patients (10{\%}) and possibly related to pSS in 14 (5{\%}). Interstitial lung disease (ILD, n = 15), especially non-specific interstitial pneumonia (n = 7), was present most commonly. In total, 16 patients (6{\%}) were scored as low (n = 4), moderate (n = 11), or high activity (n = 1) on the ESSDAI pulmonary domain. Conclusion: In this cross-sectional study in daily clinical practice, pulmonary involvement was present in 10-15{\%} of pSS patients, of which ILD was most common. Of all pSS patients, 6{\%} were scored as active on the pulmonary domain of the ESSDAI.",
keywords = "LUNG INVOLVEMENT, CLASSIFICATION CRITERIA, SYNDROME PREVALENCE, CT FINDINGS, DISEASE, MANIFESTATIONS, BRONCHIECTASIS, ABNORMALITIES, ADULTS, RISK",
author = "A. Heus and S. Arends and {Van Nimwegen}, {J. F.} and Stei, {A. J.} and Nossent, {G. D.} and H. Bootsma",
year = "2019",
month = "9",
day = "25",
doi = "10.1080/03009742.2019.1634221",
language = "English",
journal = "Scandinavian Journal of Rheumatology",
issn = "0300-9742",
publisher = "Informa Healthcare",

}

RIS

TY - JOUR

T1 - Pulmonary involvement in primary Sjogren's syndrome, as measured by the ESSDAI

AU - Heus, A.

AU - Arends, S.

AU - Van Nimwegen, J. F.

AU - Stei, A. J.

AU - Nossent, G. D.

AU - Bootsma, H.

PY - 2019/9/25

Y1 - 2019/9/25

N2 - Objective: Systemic features influence disease prognosis and choice of treatment in primary Sjogren's syndrome (pSS). Our aim was to investigate the prevalence of pulmonary involvement in pSS patients and to classify patients according to the pulmonary domain of the EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI). Methods: This retrospective cohort study included consecutive pSS patients, fulfilling American-European Consensus Group/American College of Rheumatology classification criteria, who visited the Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, in 2015. Data on pulmonary complaints and pulmonary tests were obtained from electronic patient records. Pulmonary involvement was recorded if therapy was needed or follow-up was recommended, and when it was possibly or assumed to be related to pSS instead of coincidental factors. Results: Of the 262 included pSS patients, 88 (34%) had pulmonary complaints, mostly cough or dyspnoea on exertion. Pulmonary diagnostics were performed in 225 patients (86%). Pulmonary involvement was present and assumed to be related to pSS in 25 patients (10%) and possibly related to pSS in 14 (5%). Interstitial lung disease (ILD, n = 15), especially non-specific interstitial pneumonia (n = 7), was present most commonly. In total, 16 patients (6%) were scored as low (n = 4), moderate (n = 11), or high activity (n = 1) on the ESSDAI pulmonary domain. Conclusion: In this cross-sectional study in daily clinical practice, pulmonary involvement was present in 10-15% of pSS patients, of which ILD was most common. Of all pSS patients, 6% were scored as active on the pulmonary domain of the ESSDAI.

AB - Objective: Systemic features influence disease prognosis and choice of treatment in primary Sjogren's syndrome (pSS). Our aim was to investigate the prevalence of pulmonary involvement in pSS patients and to classify patients according to the pulmonary domain of the EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI). Methods: This retrospective cohort study included consecutive pSS patients, fulfilling American-European Consensus Group/American College of Rheumatology classification criteria, who visited the Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, in 2015. Data on pulmonary complaints and pulmonary tests were obtained from electronic patient records. Pulmonary involvement was recorded if therapy was needed or follow-up was recommended, and when it was possibly or assumed to be related to pSS instead of coincidental factors. Results: Of the 262 included pSS patients, 88 (34%) had pulmonary complaints, mostly cough or dyspnoea on exertion. Pulmonary diagnostics were performed in 225 patients (86%). Pulmonary involvement was present and assumed to be related to pSS in 25 patients (10%) and possibly related to pSS in 14 (5%). Interstitial lung disease (ILD, n = 15), especially non-specific interstitial pneumonia (n = 7), was present most commonly. In total, 16 patients (6%) were scored as low (n = 4), moderate (n = 11), or high activity (n = 1) on the ESSDAI pulmonary domain. Conclusion: In this cross-sectional study in daily clinical practice, pulmonary involvement was present in 10-15% of pSS patients, of which ILD was most common. Of all pSS patients, 6% were scored as active on the pulmonary domain of the ESSDAI.

KW - LUNG INVOLVEMENT

KW - CLASSIFICATION CRITERIA

KW - SYNDROME PREVALENCE

KW - CT FINDINGS

KW - DISEASE

KW - MANIFESTATIONS

KW - BRONCHIECTASIS

KW - ABNORMALITIES

KW - ADULTS

KW - RISK

U2 - 10.1080/03009742.2019.1634221

DO - 10.1080/03009742.2019.1634221

M3 - Article

JO - Scandinavian Journal of Rheumatology

JF - Scandinavian Journal of Rheumatology

SN - 0300-9742

ER -

ID: 99699919