The dynamic niche of the foreign body reaction: messages and messengers for regenerative medicine

Luttikhuizen, D. T., 2007, Groningen: s.n.. 122 p.

Research output: ThesisThesis fully internal (DIV)Academic

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  • Daniël Theodoor Luttikhuizen
Intracorporally implanted materials, such as medical devices, will provoke the body to initiate an inflammatory reaction. This inflammatory reaction to implanted materials is known as the foreign body reaction (FBR) and is characterized by 3 distinct phases: onset, progression, and resolution. The FBR proceeds in the creation of a dynamic microenvironment that is spatially well organized. This reaction is regulated by soluble mediatiors, most likely cytokines, chemokines, and matrix metalloproteinases (MMPs), which are produced locally by surrounding tissue cells and infiltrating inflammatory cells. Zie: Summary
Original languageEnglish
QualificationDoctor of Philosophy
  • van Luyn, Marja, Supervisor
Award date3-Jan-0001
Place of PublicationGroningen
Print ISBNs9789090217444
Publication statusPublished - 2007

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