Psychological distress and salivary cortisol covary within persons during pregnancyGiesbrecht, G. F., Campbell, T., Letourneau, N., Kooistra, L., Kaplan, B. & APrON Study Team, Feb-2012, In : Psychoneuroendocrinology. 37, 2, p. 270-279 10 p.
Research output: Contribution to journal › Article › Academic › peer-review
The mechanisms whereby maternal stress during pregnancy exerts organizational effects on fetal development require elaboration. The aim of this study was to assess the plausibility of cortisol as a biological link between maternal psychological distress during pregnancy and fetal development. Previous research has resulted in equivocal findings for between-persons differences in stress and cortisol. Ecological momentary assessment was used to simultaneously assess mood and cortisol 5 times daily for 3 days in 83 women (gestational ages 6-37 weeks). Results from multilevel analysis indicated a robust within-person association between negative mood and cortisol. For each 1.0% increase in negative mood there was a corresponding 1.9% increase in cortisol. This association was unaffected by advancing gestational age. The results suggest that cortisol is a plausible biological mechanism for transducing the effects of maternal psychological distress during pregnancy to fetal development. (C) 2011 Elsevier Ltd. All rights reserved.
|Number of pages||10|
|Publication status||Published - Feb-2012|
- Pregnancy, Cortisol, Stress, Psychological distress, Anxiety, Depression, Ecological momentary assessment, Saliva, Diurnal, POSTNATAL DEPRESSION SCALE, PSYCHOSOCIAL STRESS, MATERNAL CORTISOL, MOMENTARY ASSESSMENT, PRENATAL EXPOSURE, FETAL-GROWTH, DAILY EVENTS, MOOD STATES, RESPONSES, SECRETION