Publication

Prognostic factors associated with a restricted mouth opening (trismus) in patients with head and neck cancer: Systematic review

van der Geer, S. J., van Rijn, P. V., Roodenburg, J. L. N. & Dijkstra, P. U., 18-Jun-2020, In : Journal of the Sciences and Specialties of the Head and Neck. 26 p.

Research output: Contribution to journalReview articleAcademicpeer-review

BACKGROUND: To prescribe early trismus therapy, prognostic factors influencing the restricted mouth opening should be identified first. Our aim is to present an overview of these factors in patients with head and neck cancer.

METHODS: PubMed, Cochrane, EMBASE, and CINAHL were searched using terms related to head and neck cancer and mouth opening. Risk of bias was assessed using the "Quality in Prognosis Studies" tool. A best evidence synthesis was performed.

RESULTS: Of the identified 1418 studies, 53 were included. Three studies contained a prognostic multivariate model for a restricted mouth opening.

CONCLUSIONS: Patients with head and neck cancer will most likely develop a restricted mouth opening when they have a large tumor near the masticatory muscles that requires extensive cancer treatment. A restricted mouth opening most likely occurs within 6 months after cancer treatment. Further research is necessary on factors related to healing tendency or pain intensity.

Original languageEnglish
Number of pages26
JournalJournal of the Sciences and Specialties of the Head and Neck
Publication statusPublished - 18-Jun-2020

    Keywords

  • head and neck neoplasms, mouth neoplasms, mouth opening, oral, prognosis, surgery, QUALITY-OF-LIFE, RADIATION-INDUCED TRISMUS, SQUAMOUS-CELL CARCINOMA, ORAL-CANCER, NASOPHARYNGEAL CARCINOMA, PALLIATIVE RADIOTHERAPY, OROPHARYNGEAL CANCER, HEALTH, RECONSTRUCTION, THERAPY

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