Publication

Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator

Kraai, G. N., Schuur, B., van Zwol, F., Haak, R. M., Minnaard, A. J., Feringa, B. L., Heeres, H. J. & de Vries, J. G., 2009, CATALYSIS OF ORGANIC REACTIONS. Prunier, ML. (ed.). BOCA RATON: CRC Press, Taylor and Francis Group, p. 39-49 11 p. (Chemical Industries; vol. 123).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

APA

Kraai, G. N., Schuur, B., van Zwol, F., Haak, R. M., Minnaard, A. J., Feringa, B. L., Heeres, H. J., & de Vries, J. G. (2009). Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator. In ML. Prunier (Ed.), CATALYSIS OF ORGANIC REACTIONS (pp. 39-49). (Chemical Industries; Vol. 123). CRC Press, Taylor and Francis Group.

Author

Kraai, Gerard N. ; Schuur, Boelo ; van Zwol, Floris ; Haak, Robert M. ; Minnaard, Adriaan J. ; Feringa, Ben L. ; Heeres, Hero J. ; de Vries, Johannes G. / Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator. CATALYSIS OF ORGANIC REACTIONS. editor / ML Prunier. BOCA RATON : CRC Press, Taylor and Francis Group, 2009. pp. 39-49 (Chemical Industries).

Harvard

Kraai, GN, Schuur, B, van Zwol, F, Haak, RM, Minnaard, AJ, Feringa, BL, Heeres, HJ & de Vries, JG 2009, Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator. in ML Prunier (ed.), CATALYSIS OF ORGANIC REACTIONS. Chemical Industries, vol. 123, CRC Press, Taylor and Francis Group, BOCA RATON, pp. 39-49, 22nd Conference on Catalysis of Organic Reactions, Holy See (Vatican City), 30/03/2008.

Standard

Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator. / Kraai, Gerard N.; Schuur, Boelo; van Zwol, Floris; Haak, Robert M.; Minnaard, Adriaan J.; Feringa, Ben L.; Heeres, Hero J.; de Vries, Johannes G.

CATALYSIS OF ORGANIC REACTIONS. ed. / ML Prunier. BOCA RATON : CRC Press, Taylor and Francis Group, 2009. p. 39-49 (Chemical Industries; Vol. 123).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Vancouver

Kraai GN, Schuur B, van Zwol F, Haak RM, Minnaard AJ, Feringa BL et al. Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator. In Prunier ML, editor, CATALYSIS OF ORGANIC REACTIONS. BOCA RATON: CRC Press, Taylor and Francis Group. 2009. p. 39-49. (Chemical Industries).


BibTeX

@inproceedings{0ba6de329e4245e9bcb094df2a0e74f7,
title = "Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator",
abstract = "Production of fine chemicals is mostly performed in batch reactors. Use of continuous processes has many advantages which may reduce the cost of production. We have developed the use of centrifugal contact separators (CCSs) for continuous two-phase catalytic reactions. This equipment has previously only been used for mixing and separating two liquids. We have converted Sunflower oil into biodiesel and glycerol by continuous two-phase reaction with methanolic sodium methoxide in the CCS in 96% conversion. Two-phase catalytic epoxidation was more problematic due to instability of most catalysts in a two-phase system. In a first attempt we managed to convert cyclooctene into the epoxide using hydrogen peroxide as oxidant and a tungsten-based polyoxometalate as catalyst with 20% conversion. Surprisingly, it was also possible to perform a lipase-catalysed esterification of oleic acid in the CCS. In spite of the aqueous environment a very high conversion up to 87% was reached. In this table-top device, production of 100 Kg amounts is possible in just a matter of days. Larger-sized equipment also exists that can be used for ton-scale production.",
keywords = "ORGANIC-SYNTHESIS, MICROSTRUCTURED REACTORS, MICROREACTOR TECHNOLOGY, BIODIESEL PRODUCTION, GREEN CHEMISTRY, LIQUID, EXTRACTION",
author = "Kraai, {Gerard N.} and Boelo Schuur and {van Zwol}, Floris and Haak, {Robert M.} and Minnaard, {Adriaan J.} and Feringa, {Ben L.} and Heeres, {Hero J.} and {de Vries}, {Johannes G.}",
year = "2009",
language = "English",
isbn = "978-1-4200-7076-7",
series = "Chemical Industries",
publisher = "CRC Press, Taylor and Francis Group",
pages = "39--49",
editor = "ML Prunier",
booktitle = "CATALYSIS OF ORGANIC REACTIONS",
note = "22nd Conference on Catalysis of Organic Reactions ; Conference date: 30-03-2008 Through 03-04-2008",

}

RIS

TY - GEN

T1 - Process Intensification. Continuous Two-Phase Catalytic Reactions in a Table-Top Centrifugal Contact Separator

AU - Kraai, Gerard N.

AU - Schuur, Boelo

AU - van Zwol, Floris

AU - Haak, Robert M.

AU - Minnaard, Adriaan J.

AU - Feringa, Ben L.

AU - Heeres, Hero J.

AU - de Vries, Johannes G.

PY - 2009

Y1 - 2009

N2 - Production of fine chemicals is mostly performed in batch reactors. Use of continuous processes has many advantages which may reduce the cost of production. We have developed the use of centrifugal contact separators (CCSs) for continuous two-phase catalytic reactions. This equipment has previously only been used for mixing and separating two liquids. We have converted Sunflower oil into biodiesel and glycerol by continuous two-phase reaction with methanolic sodium methoxide in the CCS in 96% conversion. Two-phase catalytic epoxidation was more problematic due to instability of most catalysts in a two-phase system. In a first attempt we managed to convert cyclooctene into the epoxide using hydrogen peroxide as oxidant and a tungsten-based polyoxometalate as catalyst with 20% conversion. Surprisingly, it was also possible to perform a lipase-catalysed esterification of oleic acid in the CCS. In spite of the aqueous environment a very high conversion up to 87% was reached. In this table-top device, production of 100 Kg amounts is possible in just a matter of days. Larger-sized equipment also exists that can be used for ton-scale production.

AB - Production of fine chemicals is mostly performed in batch reactors. Use of continuous processes has many advantages which may reduce the cost of production. We have developed the use of centrifugal contact separators (CCSs) for continuous two-phase catalytic reactions. This equipment has previously only been used for mixing and separating two liquids. We have converted Sunflower oil into biodiesel and glycerol by continuous two-phase reaction with methanolic sodium methoxide in the CCS in 96% conversion. Two-phase catalytic epoxidation was more problematic due to instability of most catalysts in a two-phase system. In a first attempt we managed to convert cyclooctene into the epoxide using hydrogen peroxide as oxidant and a tungsten-based polyoxometalate as catalyst with 20% conversion. Surprisingly, it was also possible to perform a lipase-catalysed esterification of oleic acid in the CCS. In spite of the aqueous environment a very high conversion up to 87% was reached. In this table-top device, production of 100 Kg amounts is possible in just a matter of days. Larger-sized equipment also exists that can be used for ton-scale production.

KW - ORGANIC-SYNTHESIS

KW - MICROSTRUCTURED REACTORS

KW - MICROREACTOR TECHNOLOGY

KW - BIODIESEL PRODUCTION

KW - GREEN CHEMISTRY

KW - LIQUID

KW - EXTRACTION

M3 - Conference contribution

SN - 978-1-4200-7076-7

T3 - Chemical Industries

SP - 39

EP - 49

BT - CATALYSIS OF ORGANIC REACTIONS

A2 - Prunier, ML

PB - CRC Press, Taylor and Francis Group

CY - BOCA RATON

T2 - 22nd Conference on Catalysis of Organic Reactions

Y2 - 30 March 2008 through 3 April 2008

ER -

ID: 4972151