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Predictive Factors for Rebleeding After Aneurysmal Subarachnoid Hemorrhage: Rebleeding Aneurysmal Subarachnoid Hemorrhage Study

van Donkelaar, C., Bakker, N. A., Veeger, N. J. G. M., Uyttenboogaart, M., Metzemaekers, J. D. M., Luijckx, G-J., Groen, R. J. M. & van Dijk, J. M. C., Aug-2015, In : Stroke. 46, 8, p. 2100-2106 7 p.

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  • Predictive Factors for Rebleeding After Aneurysmal Subarachnoid Hemorrhage Rebleeding Aneurysmal

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DOI

Background and Purpose-Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating type of stroke associated with high morbidity and mortality. One of the most feared complications is an early rebleeding before aneurysm repair. Predictors for such an often fatal rebleeding are largely unknown. We therefore aimed to determine predictors for an early rebleeding after aSAH in relation with time after ictus.

Methods-This observational prospective cohort study included all consecutive patients admitted with aSAH between January 1998 and December 2014 (n=1337) at our University Neurovascular Center. Clinical predictors for rebleeding

Results-A modified Fisher grade of 3 to 4 was a predictor for an in-hospital rebleeding

Conclusions-In our opinion, timing of treatment of aSAH patients, especially those with an modified Fisher grade of 3 or 4 in a good clinical condition, should be reconsidered. These aSAH patients might be regarded a medical emergency, requiring aneurysm repair as soon as possible. In this respect, our findings should provoke the debate on timing of aneurysm repair, especially in patients considered to be at high risk for rebleeding.

Original languageEnglish
Pages (from-to)2100-2106
Number of pages7
JournalStroke
Volume46
Issue number8
Publication statusPublished - Aug-2015

    Keywords

  • aneurysm, rebleeding, regression analysis, stroke, subarachnoid hemorrhage, RUPTURED INTRACRANIAL ANEURYSMS, ENDOVASCULAR COILING, CEREBRAL ANEURYSMS, TRIAL ISAT, RISK, MANAGEMENT, STROKE, DRAINAGE, OUTCOMES, COHORT

ID: 20660919