Practical introduction of novel oral anticoagulants through an anticoagulation nurse. The Leeuwarden model

Folkeringa, R. J., Geven, L. M., Veldhuis, T., Hoogendoorn, M., Hofma, S. H. & Van Roon, E., 1-Jun-2014, In : Netherlands Heart Journal. 22, 6, p. 297-300 4 p.

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  • R.J. Folkeringa
  • L.M. Geven
  • T. Veldhuis
  • M. Hoogendoorn
  • S.H. Hofma
  • E. Van Roon
Introduction: This paper describes the implementation of novel oral anticoagulants (NOACs) through an anticoagulation nurse. Logistics and tasks of this new function are described and preliminary data are presented. Methods: Indications for NOACs are explained by the treating cardiologists. Thereafter, the patient is referred to the anticoagulation nurse before starting a NOAC. After providing a patient with information and checking the creatinine clearance, co-medication and medical history, a prescription for NOAC is made. Results: In 3 months, 51 patients were referred for NOAC therapy. Mean age was 68 years, CHA2DS2-VASc score was 2.9. Renal function was impaired in 28 %. Only 63 % of the patients had an uneventful start-up. NOAC therapy was withheld or prematurely stopped in 22 %. 30 % of patients needed a reduced NOAC dose. In 37 %, the anticoagulation nurse had extended patient contact, mainly because of (presumed) side effects. Conclusion: Given the number of interactions that were made using a separate patient contact through the anticoagulation nurse, this seems to be an important improvement in the quality of care and deserves further expansion. © The Author(s) 2014.
Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalNetherlands Heart Journal
Issue number6
Publication statusPublished - 1-Jun-2014
Externally publishedYes


  • Anticoagulation, Atrial fibrillation, Novel oral anticoagulants, anticoagulant agent, dabigatran, rivaroxaban, adult, aged, anticoagulation, article, bleeding, CHADS2 score, clinical article, creatinine clearance, edema, fatigue, female, gastrointestinal symptom, glomerulus filtration rate, headache, hematoma, human, kidney function, male, pruritus, rash, stomach pain

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