Publication

Polypeptides with permease activity

Klaassen, P., De Waal, P. P., De Jong, R. M., Driessen, A. J. M., Nijland, J. G. & Shin, H. Y., 11-Dec-2014, Patent No. WO2014195520, Priority date 13-Dec-2013, Priority No. EP20130197988 20131218 ; EP20140160772 20140319 ; EP20140164270 20140410

Research output: Patent

The invention relates to a polypeptide having one or more substitution corresponding to F85T/A/C/H/M/N, T89H/D/C/A/N, V187T/C/D/E/F/G/H/K/M/Q/R/S/W/Y, A191N/G/P/ C/D/F/H/I/K/Q/V/W/Y, Y214V/Q/G/L/M/N/P/R/S, Q215L/M/I/A/C/D/F/S, I218K/N/A/C/D/E/H/L, T219G/F/D/N, I222D/C/H/E/G/P/S/V/Y, Y226D/M/R/C/G/H/I/L/P/Q/T/W, Q338C/E/F/D/G/I/P/R/S/T/V/W/Y, M339N/V/D/E/H/K/P/Q/R/Y, The invention relates to a polypeptide having one or more substitution corresponding to T89C/Y, V187M/Q/C/G/Y, A191 l/K/D/C/E/N/W/R/P, Y214L/P, Q215D/E/S/M/L/C/F/A, 1218W, T219V/L/R/E, I222G/Y/M/P/S/W, Y226M/T/P/Q, Q338R/I/D/E/F/G/P, M339Y/E/N, Q341V/Y/S/H, Q342N/H/R/C/F/G/I/K/L/P/S/T/W, L343Y/Q/I/C/E/K/N/P/S, N346G/I, N347S/L/K/G/TA/, Y350E/S/Q, G373R/K/L/IWY, N376K/Q/A/C/D/E/I/M/P, T380Y/G/M/A/S/D/E/I/K/L/W, S383Y/WA//C/E/I/L/Q/R, F446H/D/I, T448/R/K/H/D/E/W, T449F/H/A/G/I/L/P/QA/, T451W/Y/S, W455D/K/E/P/Q, N478Q/I/F/G, or W479S/I/F/D/E/H/M/N/R/T/Y of SEQ ID NO:59 wherein the polypeptide is member of the Major Facilitator Superfamily (MFS).
Original languageEnglish
Patent numberWO2014195520
Priority date13/12/2013
Publication statusPublished - 11-Dec-2014

ID: 15747673