Platelet-neutrophil interactions as drivers of inflammatory and thrombotic diseaseLisman, T., Mar-2018, In : Cell and Tissue Research. 371, 3, p. 567-576 10 p.
Research output: Contribution to journal › Review article › Academic › peer-review
Neutrophils are well known for their role in infection and inflammatory disease and are first responders at sites of infection or injury. Platelets have an established role in hemostasis and thrombosis and are first responders at sites of vascular damage. However, neutrophils are increasingly recognized for their role in thrombosis, while the immunemodulatory properties of platelets are being increasingly studied. Platelets and neutrophils interact during infection, inflammation and thrombosis and modulate each other's functions. This review will discuss the consequences of platelet-neutrophil interactions in infection, thrombosis, atherosclerosis and tissue injury and repair.
|Number of pages||10|
|Journal||Cell and Tissue Research|
|Publication status||Published - Mar-2018|
- Platelet, Neutrophil, Inflammation, Thrombosis, Ischemia, ISCHEMIA-REPERFUSION INJURY, VON-WILLEBRAND-FACTOR, DEEP-VEIN THROMBOSIS, MURINE ACETAMINOPHEN HEPATOTOXICITY, PROTEASE-ACTIVATED RECEPTOR-4, EXTRACELLULAR TRAP FORMATION, TISSUE FACTOR EXPRESSION, ACUTE CORONARY SYNDROME, IMPAIRS HOST-DEFENSE, INDUCED LIVER-INJURY