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Plasma hemopexin as a potential regulator of vascular responsiveness to angiotensin II

Bakker, W. W., Spaans, F., el Bakkali, L., Borghuis, T., van Goor, H., van Dijk, E., Buijnink, J. & Faas, M. M., Mar-2013, In : Reproductive Sciences. 20, 3, p. 234-237 4 p.

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DOI

This brief review focuses on the functional activities of plasma hemopexin recently recognized by several authors. In particular, the protease-like activity of hemopexin in vitro is linked with downregulation of the vascular angiotensin II receptor in vivo, leading to vascular expansion. Also a potential mechanism of inhibition of hemopexin activity by extracellular adenosine triphosphate is considered.

Original languageEnglish
Pages (from-to)234-237
Number of pages4
JournalReproductive Sciences
Volume20
Issue number3
Publication statusPublished - Mar-2013

    Keywords

  • hemopexin activity, angiotensin II receptor, vascular expansion, protease-like activity, ATP, POLYMORPHONUCLEAR LEUKOCYTES, PREECLAMPSIA, INHIBITION, PROTEINS, SERUM

ID: 2379916