Publication

pH-dependent ileocolonic drug delivery, part I: in vitro and clinical evaluation of novel systems

Broesder, A., Woerdenbag, H. J., Prins, G. H., Nguyen, D. N., Frijlink, H. W. & Hinrichs, W. L. J., Aug-2020, In : Drug Discovery Today. 25, 8, p. 1362-1373 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

After the pH dependency of novel pH-dependent ileocolonic drug delivery systems is confirmed in vitro, their performance should be evaluated in human volunteers.

Original languageEnglish
Pages (from-to)1362-1373
Number of pages12
JournalDrug Discovery Today
Volume25
Issue number8
Early online date15-Jun-2020
Publication statusPublished - Aug-2020

    Keywords

  • PHARMACEUTICAL DOSAGE FORMS, SMALL-INTESTINAL TRANSIT, GASTROINTESTINAL TRANSIT, INTRALUMINAL PH, ULCERATIVE-COLITIS, SULFAPYRIDINE APPEARANCE, 5-AMINOSALICYLIC ACID, INTRAGASTRIC ACIDITY, RESPONSIVE POLYMERS, GAMMA-SCINTIGRAPHY

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