PET Imaging of Myocardial β-Adrenoceptors

Slart, R., van der Meer, P., Tio, R., van Veldhuisen, D. & Elsinga, P. H., 2015, Autonomic Innervation of the Heart: Role of Molecular Imaging. Slart, R. H. J. A., Tio, R. A., Elsinga, P. H. & Schwaiger, M. (eds.). Springer, p. 235-253 451 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed.

Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.
Original languageEnglish
Title of host publicationAutonomic Innervation of the Heart
Subtitle of host publicationRole of Molecular Imaging
EditorsR H J A Slart, R A Tio, P H Elsinga, M Schwaiger
Number of pages451
ISBN (Electronic)978-3-662-45074-1
Publication statusPublished - 2015

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