Pericardial synovial sarcoma: 14-year survival with multimodality therapy

Van der Mieren, G., Willems, S., Sciot, R., Dumez, H., Van Oosterom, A., Flameng, W. & Herijgers, P., Sep-2004, In : Annals of thoracic surgery. 78, 3, p. e41-e42 2 p.

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  • Pericardial synovial sarcoma

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  • Gerry Van der Mieren
  • Stefan Willems
  • Raf Sciot
  • Herlinde Dumez
  • Allan Van Oosterom
  • Willem Flameng
  • Paul Herijgers

We report a case of recurrent primary synovial sarcoma of the pericardium. Reverse transcriptase-polymerase chain reaction analysis for t(X,18) demonstrated the presence of the chimeric transcript SYT/SSX. Because of the rarity of this entity, optimal therapy is unknown. The prognosis of this tumor is very poor in previous reports. In this report, we present a case with five recurrences treated by a combination of surgery, chemotherapy, and radiotherapy. The patient survives now for more than 14 years, the longest reported survival of a primary synovial sarcoma of the pericardium.

Original languageEnglish
Pages (from-to)e41-e42
Number of pages2
JournalAnnals of thoracic surgery
Issue number3
Publication statusPublished - Sep-2004
Externally publishedYes


  • Adult, Chemotherapy, Adjuvant, Dimethoate/administration & dosage, Disease Progression, Doxorubicin/administration & dosage, Drug Administration Schedule, Humans, Ifosfamide/administration & dosage, Isoquinolines/administration & dosage, Magnetic Resonance Imaging, Male, Mediastinal Neoplasms/diagnosis, Neoplasm Recurrence, Local/diagnosis, Neoplasm, Residual/drug therapy, Palliative Care, Pericardium/diagnostic imaging, Sarcoma, Synovial/diagnosis, Tomography, X-Ray Computed, Treatment Outcome

ID: 126027849