Publication

Patterns of pathological firing in human motor units

Thomas, CK., Butler, JE. & Zijdewind, I., 2002, SENSORIMOTOR CONTROL OF MOVEMENT AND POSTURE. Gandevia, SC., Proske, U. & Stuart, DG. (eds.). NEW YORK: Kluwer Academic/Plenum Publishers, p. 237-244 8 p. (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY; vol. 508).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Modulation of motor unit firing rates can change muscle force production. Motor unit firing rates are often reduced during voluntary contractions of muscles influenced by disorders such as stroke or multiple sclerosis, while higher firing rates are topical of muscles innervated by a reduced number of motoneurones. An expanded range of motor unit firing rates is characteristic of disorders in which damage to various systems and neurons occur. Most neuromuscular disorders result in an increase in motor unit discharge variability, in part due to a higher incidence of doublets. In spinal cord injured subjects, long lasting involuntary contractions are common. This activity may reflect persistent inward currents that are revealed due to a lack of (voluntary) inhibition. Some of these changes in motor unit behaviour may actually work to enhance muscle force rather than to reduce it.

Original languageEnglish
Title of host publicationSENSORIMOTOR CONTROL OF MOVEMENT AND POSTURE
EditorsSC Gandevia, U Proske, DG Stuart
Place of PublicationNEW YORK
PublisherKluwer Academic/Plenum Publishers
Pages237-244
Number of pages8
ISBN (Print)0-306-47285-6
Publication statusPublished - 2002
EventConference on Neural Mechanisms of Sensorimotor Control - , Australia
Duration: 3-Sep-20016-Sep-2001

Publication series

NameADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
PublisherKLUWER ACADEMIC/PLENUM PUBL
Volume508
ISSN (Print)0065-2598

Other

OtherConference on Neural Mechanisms of Sensorimotor Control
CountryAustralia
Period03/09/200106/09/2001

Event

Conference on Neural Mechanisms of Sensorimotor Control

03/09/200106/09/2001

Australia

Event: Other

    Keywords

  • SPINAL-CORD INJURY, HUMAN THENAR MUSCLES, CONTRACTILE PROPERTIES, VOLUNTARY CONTRACTION, PARKINSONS-DISEASE, HUMAN MOTONEURONS, NEUROMUSCULAR DISORDERS, ELECTRICAL-ACTIVITY, PLATEAU POTENTIALS, DISCHARGE PATTERN

ID: 4037703