Patients with Diffuse Axonal Injury Can Recover to a Favorable Long-Term Functional and Quality of Life Outcomevan Eijck, M., van der Naalt, J., de Jongh, M., Schoonman, G., Oldenbeuving, A., Peluso, J., de Vries, J. & Roks, G., Oct-2018, In : Journal of Neurotrauma. 35, 20, p. 2357-2364 8 p.
Research output: Contribution to journal › Article › Academic › peer-review
Functional outcome and quality of life are difficult to predict in patients with diffuse axonal injury (DAI) after traumatic brain injury (TBI). The primary aim of this cross-sectional cohort study was to assess the long-term functional outcome in patients with DAI and to identify prognostic factors. Second, health-related quality of life (HRQL) at long-term follow-up was assessed. Patients >= 16 years of age with TBI and DAI (admitted 2008-2014) were included. Clinical and imaging data were collected. The primary outcome parameter was the Glasgow Outcome Scale Extended (GOSE) at long-term follow-up. Second, the HRQL was assessed with the Quality Of Life after Brain Injury (QOLIBRI) questionnaire. DAI was diagnosed in 185 patients. Long-term functional outcome was obtained in 134 patients (72%), median follow-up was 54 months (range 14-100); and 51% had a favorable outcome (GOSE 6-8). Independent prognostic factors were age, pupillary reaction, Hb, DAI grading, and return of consciousness
|Number of pages||8|
|Journal||Journal of Neurotrauma|
|Publication status||Published - Oct-2018|
- DAI, GOSE, HRQL, QOLIBRI, TBI, TRAUMATIC BRAIN-INJURY, CLOSED-HEAD INJURY, LONGITUDINAL MRI, CORPUS-CALLOSUM, LESIONS, PROGNOSIS, MODERATE, PREDICTION, IMPACT, SCALE