Publication

Pathogenesis of Sjögren's

Dumusc, A., Barone, F., Nayar, S., Vissink, A., Fisher, B. A. & Bowman, S. J., 18-Oct-2018, Dubois' Lupus Erythematosus and Related Syndromes. Wallace, D. J. & Hahn, B. H. (eds.). 9th ed. Elsevier, p. 338-339 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

APA

Dumusc, A., Barone, F., Nayar, S., Vissink, A., Fisher, B. A., & Bowman, S. J. (2018). Pathogenesis of Sjögren's. In D. J. Wallace, & B. H. Hahn (Eds.), Dubois' Lupus Erythematosus and Related Syndromes (9th ed., pp. 338-339). Elsevier.

Author

Dumusc, Alexandre ; Barone, Francesca ; Nayar, Saba ; Vissink, Arjan ; Fisher, Benjamin A. ; Bowman, Simon J. / Pathogenesis of Sjögren's. Dubois' Lupus Erythematosus and Related Syndromes. editor / Daniel J. Wallace ; Bevra Hannahs Hahn. 9th. ed. Elsevier, 2018. pp. 338-339

Harvard

Dumusc, A, Barone, F, Nayar, S, Vissink, A, Fisher, BA & Bowman, SJ 2018, Pathogenesis of Sjögren's. in DJ Wallace & BH Hahn (eds), Dubois' Lupus Erythematosus and Related Syndromes. 9th edn, Elsevier, pp. 338-339.

Standard

Pathogenesis of Sjögren's. / Dumusc, Alexandre ; Barone, Francesca; Nayar, Saba ; Vissink, Arjan; Fisher, Benjamin A.; Bowman, Simon J.

Dubois' Lupus Erythematosus and Related Syndromes. ed. / Daniel J. Wallace; Bevra Hannahs Hahn. 9th. ed. Elsevier, 2018. p. 338-339.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Vancouver

Dumusc A, Barone F, Nayar S, Vissink A, Fisher BA, Bowman SJ. Pathogenesis of Sjögren's. In Wallace DJ, Hahn BH, editors, Dubois' Lupus Erythematosus and Related Syndromes. 9th ed. Elsevier. 2018. p. 338-339


BibTeX

@inbook{3a8fcb0729cd4e7e9362b9c7090ecd28,
title = "Pathogenesis of Sj{\"o}gren's",
abstract = "The pathogenesis of primary Sj{\"o}gren's (pSS) remains an area of intense research. A triggering factor, either endogenous, leading to autoantigen release, or an external factor such as a virus, is thought to trigger inflammation of the ductal epithelial cells (autoimmune epitheliitis) and chronic focal inflammation of exocrine glands by inflammatory cells with a consequential reduction in glandular function. There is also a strong genetic link between HLA-DR3 and high levels of anti-Ro/La antibodies. More recently, gene association studies have confirmed this along with associations with genes involved in B-cell activation, type-I interferons, IL-12 and the innate immune system. Other immunological studies have also identified mechanisms of B and T-cell activation, activation of the type-I interferon pathway and a potential role for epigenetics in the pathogenesis of primary SS.",
author = "Alexandre Dumusc and Francesca Barone and Saba Nayar and Arjan Vissink and Fisher, {Benjamin A.} and Bowman, {Simon J.}",
year = "2018",
month = "10",
day = "18",
language = "English",
isbn = "9780323479271",
pages = "338--339",
editor = "Wallace, {Daniel J. } and Hahn, {Bevra Hannahs }",
booktitle = "Dubois' Lupus Erythematosus and Related Syndromes",
publisher = "Elsevier",
edition = "9th",

}

RIS

TY - CHAP

T1 - Pathogenesis of Sjögren's

AU - Dumusc, Alexandre

AU - Barone, Francesca

AU - Nayar, Saba

AU - Vissink, Arjan

AU - Fisher, Benjamin A.

AU - Bowman, Simon J.

PY - 2018/10/18

Y1 - 2018/10/18

N2 - The pathogenesis of primary Sjögren's (pSS) remains an area of intense research. A triggering factor, either endogenous, leading to autoantigen release, or an external factor such as a virus, is thought to trigger inflammation of the ductal epithelial cells (autoimmune epitheliitis) and chronic focal inflammation of exocrine glands by inflammatory cells with a consequential reduction in glandular function. There is also a strong genetic link between HLA-DR3 and high levels of anti-Ro/La antibodies. More recently, gene association studies have confirmed this along with associations with genes involved in B-cell activation, type-I interferons, IL-12 and the innate immune system. Other immunological studies have also identified mechanisms of B and T-cell activation, activation of the type-I interferon pathway and a potential role for epigenetics in the pathogenesis of primary SS.

AB - The pathogenesis of primary Sjögren's (pSS) remains an area of intense research. A triggering factor, either endogenous, leading to autoantigen release, or an external factor such as a virus, is thought to trigger inflammation of the ductal epithelial cells (autoimmune epitheliitis) and chronic focal inflammation of exocrine glands by inflammatory cells with a consequential reduction in glandular function. There is also a strong genetic link between HLA-DR3 and high levels of anti-Ro/La antibodies. More recently, gene association studies have confirmed this along with associations with genes involved in B-cell activation, type-I interferons, IL-12 and the innate immune system. Other immunological studies have also identified mechanisms of B and T-cell activation, activation of the type-I interferon pathway and a potential role for epigenetics in the pathogenesis of primary SS.

M3 - Chapter

SN - 9780323479271

SP - 338

EP - 339

BT - Dubois' Lupus Erythematosus and Related Syndromes

A2 - Wallace, Daniel J.

A2 - Hahn, Bevra Hannahs

PB - Elsevier

ER -

ID: 79451760