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Parental Age and Offspring Childhood Mental Health: A Multi-Cohort, Population-Based Investigation
Zondervan-Zwijnenburg, M. A. J., Veldkamp, S. A. M., Neumann, A., Barzeva, S. A., Nelemans, S. A., van Beijsterveldt, C. E. M., Branje, S. J. T., Hillegers, M. H. J., Meeus, W. H. J., Tiemeier, H., Hoijtink, H. J. A., Oldehinkel, A. J. & Boomsma, D. I., 31-Jul-2019, In : Child Development. 19 p.Research output: Contribution to journal › Article › Academic › peer-review
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Parental Age and Offspring Childhood Mental Health : A Multi-Cohort, Population-Based Investigation. / Zondervan-Zwijnenburg, Maria A J; Veldkamp, Sabine A M; Neumann, Alexander; Barzeva, Stefania A; Nelemans, Stefanie A; van Beijsterveldt, Catharina E M; Branje, Susan J T; Hillegers, Manon H J; Meeus, Wim H J; Tiemeier, Henning; Hoijtink, Herbert J A; Oldehinkel, Albertine J; Boomsma, Dorret I.
In: Child Development, 31.07.2019.Research output: Contribution to journal › Article › Academic › peer-review
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TY - JOUR
T1 - Parental Age and Offspring Childhood Mental Health
T2 - A Multi-Cohort, Population-Based Investigation
AU - Zondervan-Zwijnenburg, Maria A J
AU - Veldkamp, Sabine A M
AU - Neumann, Alexander
AU - Barzeva, Stefania A
AU - Nelemans, Stefanie A
AU - van Beijsterveldt, Catharina E M
AU - Branje, Susan J T
AU - Hillegers, Manon H J
AU - Meeus, Wim H J
AU - Tiemeier, Henning
AU - Hoijtink, Herbert J A
AU - Oldehinkel, Albertine J
AU - Boomsma, Dorret I
N1 - © 2019 The Authors Child Development published by Wiley Periodicals, Inc. on behalf of Society for Research in Child Development.
PY - 2019/7/31
Y1 - 2019/7/31
N2 - To examine the contributions of maternal and paternal age on offspring externalizing and internalizing problems, this study analyzed problem behaviors at age 10-12 years from four Dutch population-based cohorts (N = 32,892) by a multiple informant design. Bayesian evidence synthesis was used to combine results across cohorts with 50% of the data analyzed for discovery and 50% for confirmation. There was evidence of a robust negative linear relation between parental age and externalizing problems as reported by parents. In teacher-reports, this relation was largely explained by parental socio-economic status. Parental age had limited to no association with internalizing problems. Thus, in this large population-based study, either a beneficial or no effect of advanced parenthood on child problem behavior was observed.
AB - To examine the contributions of maternal and paternal age on offspring externalizing and internalizing problems, this study analyzed problem behaviors at age 10-12 years from four Dutch population-based cohorts (N = 32,892) by a multiple informant design. Bayesian evidence synthesis was used to combine results across cohorts with 50% of the data analyzed for discovery and 50% for confirmation. There was evidence of a robust negative linear relation between parental age and externalizing problems as reported by parents. In teacher-reports, this relation was largely explained by parental socio-economic status. Parental age had limited to no association with internalizing problems. Thus, in this large population-based study, either a beneficial or no effect of advanced parenthood on child problem behavior was observed.
KW - ADVANCED PATERNAL AGE
KW - OLDER MATERNAL AGE
KW - DE-NOVO MUTATIONS
KW - PROBLEM BEHAVIOR
KW - RISK
KW - INFORMANT
KW - CHILDREN
KW - ASSOCIATIONS
KW - DEPRESSION
KW - DISORDERS
U2 - 10.1111/cdev.13267
DO - 10.1111/cdev.13267
M3 - Article
C2 - 31364163
JO - Child Development
JF - Child Development
SN - 0009-3920
ER -
ID: 92780111