Publication

Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom

Wind, L. J. N., van der Velden, A. W. G., Diercks, G. F. H., Pas, H. & Jonkman, M. F., 2010, In : Nederlands Tijdschrift voor Geneeskunde. 154, p. A2183

Research output: Contribution to journalArticleAcademicpeer-review

APA

Wind, L. J. N., van der Velden, A. W. G., Diercks, G. F. H., Pas, H., & Jonkman, M. F. (2010). Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom. Nederlands Tijdschrift voor Geneeskunde, 154, A2183.

Author

Wind, Lynnda J N ; van der Velden, Annette W G ; Diercks, Gilles F H ; Pas, Hendrikus ; Jonkman, Marcel F. / Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom. In: Nederlands Tijdschrift voor Geneeskunde. 2010 ; Vol. 154. pp. A2183.

Harvard

Wind, LJN, van der Velden, AWG, Diercks, GFH, Pas, H & Jonkman, MF 2010, 'Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom', Nederlands Tijdschrift voor Geneeskunde, vol. 154, pp. A2183.

Standard

Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom. / Wind, Lynnda J N; van der Velden, Annette W G; Diercks, Gilles F H; Pas, Hendrikus; Jonkman, Marcel F.

In: Nederlands Tijdschrift voor Geneeskunde, Vol. 154, 2010, p. A2183.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Wind LJN, van der Velden AWG, Diercks GFH, Pas H, Jonkman MF. Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom. Nederlands Tijdschrift voor Geneeskunde. 2010;154:A2183.


BibTeX

@article{ce51468bc0444cc7861a76046540a89a,
title = "Paraneoplastische pemfigus bij een pati{\"e}nt met een non-hodgkinlymfoom",
abstract = "A 53-year-old man with non-Hodgkin lymphoma developed red, flaky skin, which was initially suggestive of a drug reaction. He also had pneumonia, for which he was admitted for antibiotic treatment. During admission the skin picture changed and blisters and erosions appeared on his body. Skin biopsy and immunological examination led to the diagnosis of paraneoplastic pemphigus (PNP). The patient died five months after the diagnosis of PNP due to PNP pneumonia. PNP is a rare and often aggressive bullous disease with an autoimmune pathogenesis, associated with underlying lymphoproliferative disease. It is characterised by a polymorphous skin rash, painful mucosal erosions, sometimes with respiratory complications due to bronchiolitis obliterans. Diagnosis is based on clinical, histological and immunological findings. The prognosis is unfavourable; death occurs in 90 percent of patients. This case illustrates the importance of histology, immunofluorescence microscopy, and immunoserology in misunderstood skin disorders in patients with lymphoproliferative disease.",
keywords = "Fatal Outcome, Humans, Lymphoma, Non-Hodgkin, Male, Middle Aged, Paraneoplastic Syndromes, Pemphigus, Pneumonia, Prognosis",
author = "Wind, {Lynnda J N} and {van der Velden}, {Annette W G} and Diercks, {Gilles F H} and Hendrikus Pas and Jonkman, {Marcel F}",
year = "2010",
language = "Dutch",
volume = "154",
pages = "A2183",
journal = "Nederlands Tijdschrift voor Geneeskunde",
issn = "0028-2162",
publisher = "NLM (Medline)",

}

RIS

TY - JOUR

T1 - Paraneoplastische pemfigus bij een patiënt met een non-hodgkinlymfoom

AU - Wind, Lynnda J N

AU - van der Velden, Annette W G

AU - Diercks, Gilles F H

AU - Pas, Hendrikus

AU - Jonkman, Marcel F

PY - 2010

Y1 - 2010

N2 - A 53-year-old man with non-Hodgkin lymphoma developed red, flaky skin, which was initially suggestive of a drug reaction. He also had pneumonia, for which he was admitted for antibiotic treatment. During admission the skin picture changed and blisters and erosions appeared on his body. Skin biopsy and immunological examination led to the diagnosis of paraneoplastic pemphigus (PNP). The patient died five months after the diagnosis of PNP due to PNP pneumonia. PNP is a rare and often aggressive bullous disease with an autoimmune pathogenesis, associated with underlying lymphoproliferative disease. It is characterised by a polymorphous skin rash, painful mucosal erosions, sometimes with respiratory complications due to bronchiolitis obliterans. Diagnosis is based on clinical, histological and immunological findings. The prognosis is unfavourable; death occurs in 90 percent of patients. This case illustrates the importance of histology, immunofluorescence microscopy, and immunoserology in misunderstood skin disorders in patients with lymphoproliferative disease.

AB - A 53-year-old man with non-Hodgkin lymphoma developed red, flaky skin, which was initially suggestive of a drug reaction. He also had pneumonia, for which he was admitted for antibiotic treatment. During admission the skin picture changed and blisters and erosions appeared on his body. Skin biopsy and immunological examination led to the diagnosis of paraneoplastic pemphigus (PNP). The patient died five months after the diagnosis of PNP due to PNP pneumonia. PNP is a rare and often aggressive bullous disease with an autoimmune pathogenesis, associated with underlying lymphoproliferative disease. It is characterised by a polymorphous skin rash, painful mucosal erosions, sometimes with respiratory complications due to bronchiolitis obliterans. Diagnosis is based on clinical, histological and immunological findings. The prognosis is unfavourable; death occurs in 90 percent of patients. This case illustrates the importance of histology, immunofluorescence microscopy, and immunoserology in misunderstood skin disorders in patients with lymphoproliferative disease.

KW - Fatal Outcome

KW - Humans

KW - Lymphoma, Non-Hodgkin

KW - Male

KW - Middle Aged

KW - Paraneoplastic Syndromes

KW - Pemphigus

KW - Pneumonia

KW - Prognosis

M3 - Article

C2 - 21176265

VL - 154

SP - A2183

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

SN - 0028-2162

ER -

ID: 17444929