'PARAMEDIC-2: Big study, small result'

ter Avest, E. & Lameijer, H., Jul-2019, In : Netherlands Heart Hournal. 27, 7-8, p. 341-342 2 p.

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The PARAMEDIC-2 trial demonstrated that the use of adrenaline compared with placebo in out-of-hospital cardiac arrest (OHCA) resulted in asmall increase in 30-day survival, but was associated with ahigher number of survivors with severe neurological impairment. These findings received alot of attention, and generated awidespread discussion about the role of adrenaline in cardiac arrest. In this point of view, we aim to place the PARAMEDIC-2 results in the right perspective by comparing the relative effect of adrenaline to other determinants of cerebral blood flow.

Original languageEnglish
Pages (from-to)341-342
Number of pages2
JournalNetherlands Heart Hournal
Issue number7-8
Publication statusPublished - Jul-2019


  • Adrenaline, Out-of-hospital cardiac arrest, OHCA

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