Paclitaxel prodrugs, method for preparation as well as their use in selective chemotherapyde Bont, H. BA., Leenders, R. GG., Scheeren, J. W., Haisma, H. J. & de Vos, D., 2-Jun-1998, IPC No. C07H 13/ 12 A I, Patent No. US5760072, Priority date 29-Dec-1995, Priority No. EP19950203671
Research output: Patent › Professional
A paclitaxel prodrug has a paclitaxel portion coupled to a cleavable N-(aliphatic or aromatic)-O-glycosyl carbamate spacer group, and can be administered orally, topically or by injection to provide an anti-tumor effect, the prodrug being activated by a hydrolizing enzyme, an endogeneous enzyme or an exogeneous enzyme.
|IPC||C07H 13/ 12 A I|
|Publication status||Published - 2-Jun-1998|