p24 proteins play a role in peroxisome proliferation in yeastKurbatova, E., Otzen, M. & van der Klei, I. J., 6-Oct-2009, In : FEBS Letters. 583, 19, p. 3175-3180 6 p.
Research output: Contribution to journal › Article › Academic › peer-review
Emp24 is a member of the p24 protein family, which was initially localized to the endoplasmic reticulum, Golgi and COP vesicles, but has recently shown to be associated with Saccharomyces cerevisiae peroxisomes as well. Using cell fractionation and electron- and fluorescence microscopy, we show that in the yeast Hansenula polymorpha, Emp24 also associates with peroxisomes. In addition, we show that peroxisome numbers are strongly decreased in H. polymorpha cells lacking two proteins of the p24 complex, Emp24 and Erp3. Detailed fluorescence microscopy analyses suggest that emp24. erp3 cells are disturbed in peroxisome fission and inheritance. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
|Number of pages||6|
|Publication status||Published - 6-Oct-2009|
- Organelle proliferation, Endoplasmic reticulum, Peroxisome, Organelle fission, HANSENULA-POLYMORPHA, SACCHAROMYCES-CEREVISIAE, TRANSPORT, MEMBRANE, FISSION, COMPLEX, CELLS, PEX3P