Publication

Oxygen therapy for sepsis patients in the emergency department: A little less?

Stolmeijer, R., ter Maaten, J. C., Zijlstra, J. G. & Ligtenberg, J. J. M., Jun-2014, In : European journal of emergency medicine. 21, 3, p. 233-235 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Copy link to clipboard

Documents

  • Oxygen therapy for sepsis patients in the emergency department a little less

    Final publisher's version, 163 KB, PDF document

DOI

Liberal oxygen therapy has been a cornerstone in the treatment of critically ill patients. Recently, awareness of hyperoxia toxicity has emerged. We investigated the partial pressure of oxygen in arterial blood (PaO2) in sepsis patients admitted to the emergency department treated with a reduced inspired oxygen fraction of 0.4 instead of 0.6-0.8. A prospective pilot study was carried out over a 3-month period. Patients admitted with two or more SIRS criteria and a suspicion of infection were included. They received 10 l O-2/min through a VentiMask 40%. Of 83 patients, 77 had a PaO2 greater than 9.5 kPa with 10 l O-2/min, of whom 51 had hyperoxia. Six patients showed hypoxia with 10 l O-2/min. Of the hyperoxic patients, 8% died in hospital versus 6% with normoxia. Less than 8% of patients had hypoxia with 10 l O-2/min; 66% were hyperoxic. Titration of oxygen therapy to normoxia in the emergency department should be evaluated.

Original languageEnglish
Pages (from-to)233-235
Number of pages3
JournalEuropean journal of emergency medicine
Volume21
Issue number3
Publication statusPublished - Jun-2014

    Keywords

  • sepsis, hyperoxia, emergency department, oxygen, IN-HOSPITAL MORTALITY, CARDIAC-ARREST, ARTERIAL HYPEROXIA, RESUSCITATION

ID: 13844990