Publication

Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer: A Systematic Review

Bruns, E. R. J., Argillander, T. E., Van den Heuvel, B., Buskens, C. J., Van Duijvendijk, P., Winkels, R. M., Kalf, A., Van der Zaag, E. S., Wassenaar, E. B., Bemelman, W. A. & Van Munster, B. C., Jan-2018, In : Surgical Infections. 19, 1, p. 1-10 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Bruns, E. R. J., Argillander, T. E., Van den Heuvel, B., Buskens, C. J., Van Duijvendijk, P., Winkels, R. M., Kalf, A., Van der Zaag, E. S., Wassenaar, E. B., Bemelman, W. A., & Van Munster, B. C. (2018). Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer: A Systematic Review. Surgical Infections, 19(1), 1-10. https://doi.org/10.1089/sur.2017.143

Author

Bruns, Emma R. J. ; Argillander, Tanja E. ; Van den Heuvel, Baukje ; Buskens, Christianne J. ; Van Duijvendijk, Peter ; Winkels, Renate M. ; Kalf, Annette ; Van der Zaag, Edwin S. ; Wassenaar, Eelco B. ; Bemelman, Willem A. ; Van Munster, Barbara C. / Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer : A Systematic Review. In: Surgical Infections. 2018 ; Vol. 19, No. 1. pp. 1-10.

Harvard

Bruns, ERJ, Argillander, TE, Van den Heuvel, B, Buskens, CJ, Van Duijvendijk, P, Winkels, RM, Kalf, A, Van der Zaag, ES, Wassenaar, EB, Bemelman, WA & Van Munster, BC 2018, 'Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer: A Systematic Review', Surgical Infections, vol. 19, no. 1, pp. 1-10. https://doi.org/10.1089/sur.2017.143

Standard

Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer : A Systematic Review. / Bruns, Emma R. J.; Argillander, Tanja E.; Van den Heuvel, Baukje; Buskens, Christianne J.; Van Duijvendijk, Peter; Winkels, Renate M.; Kalf, Annette; Van der Zaag, Edwin S.; Wassenaar, Eelco B.; Bemelman, Willem A.; Van Munster, Barbara C.

In: Surgical Infections, Vol. 19, No. 1, 01.2018, p. 1-10.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Bruns ERJ, Argillander TE, Van den Heuvel B, Buskens CJ, Van Duijvendijk P, Winkels RM et al. Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer: A Systematic Review. Surgical Infections. 2018 Jan;19(1):1-10. https://doi.org/10.1089/sur.2017.143


BibTeX

@article{fb96a11e62794f31847a4e3cad9656e3,
title = "Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer: A Systematic Review",
abstract = "Background: Nutritional status has major impacts on the outcome of surgery, in particular in patients with cancer. The aim of this review was to assess the merit of oral pre-operative nutritional support as a part of prehabilitation in patients undergoing surgery for colorectal cancer. Methods: A systematic literature search and meta-analysis was performed according to the Preferred Reporting of Systematic Reviews and Meta-Analyses (PRISMA) recommendations in order to review all trials investigating the effect of oral pre-operative nutritional support in patients undergoing colorectal surgery. The primary outcome was overall complication rate. Secondary outcomes were incision infection rate, anastomotic leakage rate, and length of hospital stay. Results: Five randomized controlled trials and one controlled trial were included. The studies contained a total of 583 patients with an average age of 63y (range 23-88y), of whom 87% had colorectal cancer. Malnourishment rates ranged from 8%-68%. All investigators provided an oral protein supplement. Overall patient compliance rates ranged from 72%-100%. There was no significant reduction in the overall complication rate in the interventional groups (odds ratio 0.82; 95% confidence interval 0.52-1.25). Conclusion: Current studies are too heterogeneous to conclude that pre-operative oral nutritional support could enhance the condition of patients undergoing colorectal surgery. Patients at risk have a relatively lean body mass deficit (sarcopenia) rather than an absolute malnourished status. Compliance is an important element of prehabilitation. Targeting patients at risk, combining protein supplements with strength training, and defining standardized patient-related outcomes will be essential to obtain satisfactory results.",
keywords = "colorectal cancer, nutrition, prehabilitation, surgery, POSTOPERATIVE COMPLICATIONS, ENTERAL IMMUNONUTRITION, PHYSICAL PERFORMANCE, RESECTION SURGERY, CONTROLLED-TRIAL, OLDER PATIENTS, MUSCLE MASS, SARCOPENIA, RECOVERY, EXERCISE",
author = "Bruns, {Emma R. J.} and Argillander, {Tanja E.} and {Van den Heuvel}, Baukje and Buskens, {Christianne J.} and {Van Duijvendijk}, Peter and Winkels, {Renate M.} and Annette Kalf and {Van der Zaag}, {Edwin S.} and Wassenaar, {Eelco B.} and Bemelman, {Willem A.} and {Van Munster}, {Barbara C.}",
year = "2018",
month = jan,
doi = "10.1089/sur.2017.143",
language = "English",
volume = "19",
pages = "1--10",
journal = "Surgical Infections",
issn = "1096-2964",
publisher = "MARY ANN LIEBERT, INC",
number = "1",

}

RIS

TY - JOUR

T1 - Oral Nutrition as a Form of Pre-Operative Enhancement in Patients Undergoing Surgery for Colorectal Cancer

T2 - A Systematic Review

AU - Bruns, Emma R. J.

AU - Argillander, Tanja E.

AU - Van den Heuvel, Baukje

AU - Buskens, Christianne J.

AU - Van Duijvendijk, Peter

AU - Winkels, Renate M.

AU - Kalf, Annette

AU - Van der Zaag, Edwin S.

AU - Wassenaar, Eelco B.

AU - Bemelman, Willem A.

AU - Van Munster, Barbara C.

PY - 2018/1

Y1 - 2018/1

N2 - Background: Nutritional status has major impacts on the outcome of surgery, in particular in patients with cancer. The aim of this review was to assess the merit of oral pre-operative nutritional support as a part of prehabilitation in patients undergoing surgery for colorectal cancer. Methods: A systematic literature search and meta-analysis was performed according to the Preferred Reporting of Systematic Reviews and Meta-Analyses (PRISMA) recommendations in order to review all trials investigating the effect of oral pre-operative nutritional support in patients undergoing colorectal surgery. The primary outcome was overall complication rate. Secondary outcomes were incision infection rate, anastomotic leakage rate, and length of hospital stay. Results: Five randomized controlled trials and one controlled trial were included. The studies contained a total of 583 patients with an average age of 63y (range 23-88y), of whom 87% had colorectal cancer. Malnourishment rates ranged from 8%-68%. All investigators provided an oral protein supplement. Overall patient compliance rates ranged from 72%-100%. There was no significant reduction in the overall complication rate in the interventional groups (odds ratio 0.82; 95% confidence interval 0.52-1.25). Conclusion: Current studies are too heterogeneous to conclude that pre-operative oral nutritional support could enhance the condition of patients undergoing colorectal surgery. Patients at risk have a relatively lean body mass deficit (sarcopenia) rather than an absolute malnourished status. Compliance is an important element of prehabilitation. Targeting patients at risk, combining protein supplements with strength training, and defining standardized patient-related outcomes will be essential to obtain satisfactory results.

AB - Background: Nutritional status has major impacts on the outcome of surgery, in particular in patients with cancer. The aim of this review was to assess the merit of oral pre-operative nutritional support as a part of prehabilitation in patients undergoing surgery for colorectal cancer. Methods: A systematic literature search and meta-analysis was performed according to the Preferred Reporting of Systematic Reviews and Meta-Analyses (PRISMA) recommendations in order to review all trials investigating the effect of oral pre-operative nutritional support in patients undergoing colorectal surgery. The primary outcome was overall complication rate. Secondary outcomes were incision infection rate, anastomotic leakage rate, and length of hospital stay. Results: Five randomized controlled trials and one controlled trial were included. The studies contained a total of 583 patients with an average age of 63y (range 23-88y), of whom 87% had colorectal cancer. Malnourishment rates ranged from 8%-68%. All investigators provided an oral protein supplement. Overall patient compliance rates ranged from 72%-100%. There was no significant reduction in the overall complication rate in the interventional groups (odds ratio 0.82; 95% confidence interval 0.52-1.25). Conclusion: Current studies are too heterogeneous to conclude that pre-operative oral nutritional support could enhance the condition of patients undergoing colorectal surgery. Patients at risk have a relatively lean body mass deficit (sarcopenia) rather than an absolute malnourished status. Compliance is an important element of prehabilitation. Targeting patients at risk, combining protein supplements with strength training, and defining standardized patient-related outcomes will be essential to obtain satisfactory results.

KW - colorectal cancer

KW - nutrition

KW - prehabilitation

KW - surgery

KW - POSTOPERATIVE COMPLICATIONS

KW - ENTERAL IMMUNONUTRITION

KW - PHYSICAL PERFORMANCE

KW - RESECTION SURGERY

KW - CONTROLLED-TRIAL

KW - OLDER PATIENTS

KW - MUSCLE MASS

KW - SARCOPENIA

KW - RECOVERY

KW - EXERCISE

U2 - 10.1089/sur.2017.143

DO - 10.1089/sur.2017.143

M3 - Review article

VL - 19

SP - 1

EP - 10

JO - Surgical Infections

JF - Surgical Infections

SN - 1096-2964

IS - 1

ER -

ID: 62720499