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Novel compositions and methods for trehalose phospholipids

Tan-Yun, C., Buter, J., van Rhijn, I., Minnaard, A. J. & Moody, J. B., 16-Jul-2020, Patent No. WO2020146523, 8-Jan-2020, Priority date 8-Jan-2019

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Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6'-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
Original languageEnglish
Patent numberWO2020146523
Priority date08/01/2019
Filing date08/01/2020
Publication statusPublished - 16-Jul-2020

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