Publication

New Therapies in Vulvar Cancer

Oonk, M. H. M. & van der Zee, A. G. J., 22-Feb-2017, Translational Advances in Gynecologic Cancers. HANLEY & BELFUS-ELSEVIER INC, p. 303-312 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

APA

Oonk, M. H. M., & van der Zee, A. G. J. (2017). New Therapies in Vulvar Cancer. In Translational Advances in Gynecologic Cancers (pp. 303-312). HANLEY & BELFUS-ELSEVIER INC. https://doi.org/10.1016/B978-0-12-803741-6.00015-X

Author

Oonk, M. H.M. ; van der Zee, A. G.J. / New Therapies in Vulvar Cancer. Translational Advances in Gynecologic Cancers. HANLEY & BELFUS-ELSEVIER INC, 2017. pp. 303-312

Harvard

Oonk, MHM & van der Zee, AGJ 2017, New Therapies in Vulvar Cancer. in Translational Advances in Gynecologic Cancers. HANLEY & BELFUS-ELSEVIER INC, pp. 303-312. https://doi.org/10.1016/B978-0-12-803741-6.00015-X

Standard

New Therapies in Vulvar Cancer. / Oonk, M. H.M.; van der Zee, A. G.J.

Translational Advances in Gynecologic Cancers. HANLEY & BELFUS-ELSEVIER INC, 2017. p. 303-312.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Vancouver

Oonk MHM, van der Zee AGJ. New Therapies in Vulvar Cancer. In Translational Advances in Gynecologic Cancers. HANLEY & BELFUS-ELSEVIER INC. 2017. p. 303-312 https://doi.org/10.1016/B978-0-12-803741-6.00015-X


BibTeX

@inbook{324b347c615945dcbdc0d2b69cbb9b2c,
title = "New Therapies in Vulvar Cancer",
abstract = "Major advances have been made in vulvar cancer treatment during the last decades, exploring less morbid treatment options without compromising survival. The introduction of the sentinel lymph node procedure is one of the most important advances in surgical management of early-stage vulvar cancer patients, resulting in a significant decrease in treatment-related morbidity. Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V) II is currently investigating the safety of replacing inguinofemoral lymphadenectomy by radiotherapy in patients with a metastatic sentinel lymph node. Targeted therapy in vulvar cancer is still in its infancy; preliminary results from pilot studies are promising, however large studies are lacking. Since vulvar cancer originates by two different pathways, an human papillomavirus (HPV)-dependent and HPV-independent type, studies on targeted therapy should take this into account.",
keywords = "Angiogenesis, EGFR, HPV, Radiotherapy, Sentinel lymph node procedure, VEGF, Vulvar cancer",
author = "Oonk, {M. H.M.} and {van der Zee}, {A. G.J.}",
year = "2017",
month = "2",
day = "22",
doi = "10.1016/B978-0-12-803741-6.00015-X",
language = "English",
isbn = "9780128037416",
pages = "303--312",
booktitle = "Translational Advances in Gynecologic Cancers",
publisher = "HANLEY & BELFUS-ELSEVIER INC",

}

RIS

TY - CHAP

T1 - New Therapies in Vulvar Cancer

AU - Oonk, M. H.M.

AU - van der Zee, A. G.J.

PY - 2017/2/22

Y1 - 2017/2/22

N2 - Major advances have been made in vulvar cancer treatment during the last decades, exploring less morbid treatment options without compromising survival. The introduction of the sentinel lymph node procedure is one of the most important advances in surgical management of early-stage vulvar cancer patients, resulting in a significant decrease in treatment-related morbidity. Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V) II is currently investigating the safety of replacing inguinofemoral lymphadenectomy by radiotherapy in patients with a metastatic sentinel lymph node. Targeted therapy in vulvar cancer is still in its infancy; preliminary results from pilot studies are promising, however large studies are lacking. Since vulvar cancer originates by two different pathways, an human papillomavirus (HPV)-dependent and HPV-independent type, studies on targeted therapy should take this into account.

AB - Major advances have been made in vulvar cancer treatment during the last decades, exploring less morbid treatment options without compromising survival. The introduction of the sentinel lymph node procedure is one of the most important advances in surgical management of early-stage vulvar cancer patients, resulting in a significant decrease in treatment-related morbidity. Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V) II is currently investigating the safety of replacing inguinofemoral lymphadenectomy by radiotherapy in patients with a metastatic sentinel lymph node. Targeted therapy in vulvar cancer is still in its infancy; preliminary results from pilot studies are promising, however large studies are lacking. Since vulvar cancer originates by two different pathways, an human papillomavirus (HPV)-dependent and HPV-independent type, studies on targeted therapy should take this into account.

KW - Angiogenesis

KW - EGFR

KW - HPV

KW - Radiotherapy

KW - Sentinel lymph node procedure

KW - VEGF

KW - Vulvar cancer

UR - https://www.sciencedirect.com/science/article/pii/B978012803741600015X?via%3Dihub

U2 - 10.1016/B978-0-12-803741-6.00015-X

DO - 10.1016/B978-0-12-803741-6.00015-X

M3 - Chapter

SN - 9780128037416

SP - 303

EP - 312

BT - Translational Advances in Gynecologic Cancers

PB - HANLEY & BELFUS-ELSEVIER INC

ER -

ID: 112110668