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Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome

Plaat, B. E. C., Zwakenberg, M. A., van Zwol, J. G., Wedman, J., van der Laan, B. F. A. M., Halmos, G. B. & Dikkers, F. G., Jul-2017, In : Journal of the Sciences and Specialties of the Head and Neck. 39, 7, p. 1343-1348 6 p.

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  • Narrow-band imaging in transoral laser surgery forearly glottic cancer in relation to clinical outcome

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DOI

BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.

METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.

RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).

CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.

Original languageEnglish
Pages (from-to)1343-1348
Number of pages6
JournalJournal of the Sciences and Specialties of the Head and Neck
Volume39
Issue number7
Early online date29-Mar-2017
Publication statusPublished - Jul-2017

    Keywords

  • laryngeal cancer, narrow-band imaging (NBI), transoral laser surgery, SQUAMOUS-CELL CARCINOMA, EUROPEAN LARYNGOLOGICAL SOCIETY, HIGH-DEFINITION TELEVISION, RESECTION MARGINS, NECK-CANCER, NASOPHARYNGEAL CARCINOMA, LARYNGEAL-CANCER, MICROSURGERY, ENDOSCOPY, HEAD
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