Multiple Base-Recognition Sites in a Biological Nanopore: Two Heads are Better than One

Stoddart, D., Maglia, G., Mikhailova, E., Heron, A. & Bayley, H., 2010, In : Angewandte Chemie - International Edition. 49, 3, p. 556-559 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

The α-hemolysin nanopore is a promising sensor for ultra-rapid sequencing of DNA strands within nanopores. By using immobilized synthetic oligonucleotides, it is shown that additional sequence information can be gained when two recognition sites, rather than one, are employed within a single nanopore (see picture).
Original languageEnglish
Pages (from-to)556-559
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number3
Publication statusPublished - 2010
Externally publishedYes

ID: 36009637