Publication

MORPHOLOGICAL CLASSIFICATION OF RENAL-CANCER

STORKEL, S. & VANDENBERG, E., Jun-1995, In : World journal of urology. 13, 3, p. 153-158 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

  • S STORKEL
  • E VANDENBERG

The current classification of renal-cell adenomas (RCAs) and carcinomas (RCCs) is based on eight basic cell and tumor types (entities) with characteristic morphologic features: (1) RCCs of clear-cell type, (2) RCAs/RCCs of chromophilic-cell type, (3) RCAs/RCCs of chromophobic-cell type, (4) RCCs of duct Bellini type, (5) RCCs of transitional-cell type, (6) RCCs of neuroendocrine type, (7) RCAs of oncocytic type, and (8) RCAs of metanephroid type. Tumors with a proposed histogenesis from the proximal tubule (clear-cell and chromophilic tumors) amount to 85%; of renal cancers, whereas tumors with a proposed histogenesis from the connecting tubule/ collecting duct (chromophobic-, oncocytic-, and duct Bellini-type tumors) amount to only 11%. The remaining tumor types represent rare entities (less than 1% each). Tumor cytogenetics data confirm the proposed eight morphologic subtypes and give further indications for type-specific tumor development and progression.

Original languageEnglish
Pages (from-to)153-158
Number of pages6
JournalWorld journal of urology
Volume13
Issue number3
Publication statusPublished - Jun-1995

    Keywords

  • COLLECTING DUCT CARCINOMA, CELL CARCINOMA, TUMOR, ONCOCYTOMA

ID: 6426663