Publication

Moonlighting proteins: An intriguing mode of multitasking

Huberts, D. & van der Klei, I. J., Apr-2010, In : Biochimica et Biophysica Acta-Molecular Cell Research. 1803, 4, p. 520-525 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Huberts, D., & van der Klei, I. J. (2010). Moonlighting proteins: An intriguing mode of multitasking. Biochimica et Biophysica Acta-Molecular Cell Research, 1803(4), 520-525. https://doi.org/10.1016/j.bbamcr.2010.01.022

Author

Huberts, Daphne ; van der Klei, I.J. / Moonlighting proteins : An intriguing mode of multitasking. In: Biochimica et Biophysica Acta-Molecular Cell Research. 2010 ; Vol. 1803, No. 4. pp. 520-525.

Harvard

Huberts, D & van der Klei, IJ 2010, 'Moonlighting proteins: An intriguing mode of multitasking', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1803, no. 4, pp. 520-525. https://doi.org/10.1016/j.bbamcr.2010.01.022

Standard

Moonlighting proteins : An intriguing mode of multitasking. / Huberts, Daphne; van der Klei, I.J.

In: Biochimica et Biophysica Acta-Molecular Cell Research, Vol. 1803, No. 4, 04.2010, p. 520-525.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Huberts D, van der Klei IJ. Moonlighting proteins: An intriguing mode of multitasking. Biochimica et Biophysica Acta-Molecular Cell Research. 2010 Apr;1803(4):520-525. https://doi.org/10.1016/j.bbamcr.2010.01.022


BibTeX

@article{ee6b657bf56b49a08f0e7d4f758c829d,
title = "Moonlighting proteins: An intriguing mode of multitasking",
abstract = "Proteins are macromolecules, which perform a large variety of functions. Most of them have only a single function, but an increasing number of proteins are being identified as multifunctional. Moonlighting proteins form a special class of multifunctional proteins. They perform multiple autonomous and often unrelated functions without partitioning these functions into different domains of the protein. Striking examples are enzymes, which in addition to their catalytic function are involved in fully unrelated processes such as autophagy, protein transport or DNA maintenance. In this contribution we present an overview of our current knowledge of moonlighting proteins and discuss the significant implications for biomedical and fundamental research. (C) 2010 Elsevier B.V. All rights reserved.",
keywords = "Multifunctional protein, Enzyme, Moonlighting, Gene sharing, ESCHERICHIA-COLI THIOREDOXIN, T7 DEOXYRIBONUCLEIC-ACID, ELEMENT-BINDING-PROTEIN, DNA-POLYMERASE-ACTIVITY, VACUOLAR H+-ATPASE, SACCHAROMYCES-CEREVISIAE, ALCOHOL OXIDASE, MYCOBACTERIUM-TUBERCULOSIS, PYRUVATE-CARBOXYLASE, CYTOCHROME-C",
author = "Daphne Huberts and {van der Klei}, I.J.",
year = "2010",
month = "4",
doi = "10.1016/j.bbamcr.2010.01.022",
language = "English",
volume = "1803",
pages = "520--525",
journal = "Biochimica et Biophysica Acta - Molecular Cell Research",
issn = "0167-4889",
publisher = "ELSEVIER SCIENCE BV",
number = "4",

}

RIS

TY - JOUR

T1 - Moonlighting proteins

T2 - An intriguing mode of multitasking

AU - Huberts, Daphne

AU - van der Klei, I.J.

PY - 2010/4

Y1 - 2010/4

N2 - Proteins are macromolecules, which perform a large variety of functions. Most of them have only a single function, but an increasing number of proteins are being identified as multifunctional. Moonlighting proteins form a special class of multifunctional proteins. They perform multiple autonomous and often unrelated functions without partitioning these functions into different domains of the protein. Striking examples are enzymes, which in addition to their catalytic function are involved in fully unrelated processes such as autophagy, protein transport or DNA maintenance. In this contribution we present an overview of our current knowledge of moonlighting proteins and discuss the significant implications for biomedical and fundamental research. (C) 2010 Elsevier B.V. All rights reserved.

AB - Proteins are macromolecules, which perform a large variety of functions. Most of them have only a single function, but an increasing number of proteins are being identified as multifunctional. Moonlighting proteins form a special class of multifunctional proteins. They perform multiple autonomous and often unrelated functions without partitioning these functions into different domains of the protein. Striking examples are enzymes, which in addition to their catalytic function are involved in fully unrelated processes such as autophagy, protein transport or DNA maintenance. In this contribution we present an overview of our current knowledge of moonlighting proteins and discuss the significant implications for biomedical and fundamental research. (C) 2010 Elsevier B.V. All rights reserved.

KW - Multifunctional protein

KW - Enzyme

KW - Moonlighting

KW - Gene sharing

KW - ESCHERICHIA-COLI THIOREDOXIN

KW - T7 DEOXYRIBONUCLEIC-ACID

KW - ELEMENT-BINDING-PROTEIN

KW - DNA-POLYMERASE-ACTIVITY

KW - VACUOLAR H+-ATPASE

KW - SACCHAROMYCES-CEREVISIAE

KW - ALCOHOL OXIDASE

KW - MYCOBACTERIUM-TUBERCULOSIS

KW - PYRUVATE-CARBOXYLASE

KW - CYTOCHROME-C

U2 - 10.1016/j.bbamcr.2010.01.022

DO - 10.1016/j.bbamcr.2010.01.022

M3 - Article

VL - 1803

SP - 520

EP - 525

JO - Biochimica et Biophysica Acta - Molecular Cell Research

JF - Biochimica et Biophysica Acta - Molecular Cell Research

SN - 0167-4889

IS - 4

ER -

ID: 1898339