Publication

miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants

Desvignes, T., Batzel, P., Berezikov, E., Eilbeck, K., Eppig, J. T., McAndrews, M. S., Singer, A. & Postlethwait, J. H., Nov-2015, In : Trends in Genetics. 31, 11, p. 613-626 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Desvignes, T., Batzel, P., Berezikov, E., Eilbeck, K., Eppig, J. T., McAndrews, M. S., Singer, A., & Postlethwait, J. H. (2015). miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants. Trends in Genetics, 31(11), 613-626. https://doi.org/10.1016/j.tig.2015.09.002

Author

Desvignes, T. ; Batzel, P. ; Berezikov, E. ; Eilbeck, K. ; Eppig, J. T. ; McAndrews, M. S. ; Singer, A. ; Postlethwait, J. H. / miRNA Nomenclature : A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants. In: Trends in Genetics. 2015 ; Vol. 31, No. 11. pp. 613-626.

Harvard

Desvignes, T, Batzel, P, Berezikov, E, Eilbeck, K, Eppig, JT, McAndrews, MS, Singer, A & Postlethwait, JH 2015, 'miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants', Trends in Genetics, vol. 31, no. 11, pp. 613-626. https://doi.org/10.1016/j.tig.2015.09.002

Standard

miRNA Nomenclature : A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants. / Desvignes, T.; Batzel, P.; Berezikov, E.; Eilbeck, K.; Eppig, J. T.; McAndrews, M. S.; Singer, A.; Postlethwait, J. H.

In: Trends in Genetics, Vol. 31, No. 11, 11.2015, p. 613-626.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Desvignes T, Batzel P, Berezikov E, Eilbeck K, Eppig JT, McAndrews MS et al. miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants. Trends in Genetics. 2015 Nov;31(11):613-626. https://doi.org/10.1016/j.tig.2015.09.002


BibTeX

@article{f0df8e6d757a4ebab7d35bf76a8928b2,
title = "miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants",
abstract = "High-throughput sequencing of miRNAs has revealed the diversity and variability of mature and functional short noncoding RNAs, including their genomic origins, biogenesis pathways, sequence variability, and newly identified products such as miRNA-offset RNAs (moRs). Here we review known cases of alternative mature miRNA-like RNA fragments and propose a revised definition of miRNAs to encompass this diversity. We then review nomenclature guidelines for miRNAs and propose to extend nomenclature conventions to align with those for protein-coding genes established by international consortia. Finally, we suggest a system to encompass the full complexity of sequence variations (i.e., isomiRs) in the analysis of small RNA sequencing experiments.",
keywords = "PIWI-INTERACTING RNAS, MICRORNA-OFFSET RNAS, ANIMAL MICRORNAS, REGULATORY RNAS, NONCODING RNAS, STEM-CELLS, Y RNAS, BIOGENESIS, EVOLUTION, ANNOTATION",
author = "T. Desvignes and P. Batzel and E. Berezikov and K. Eilbeck and Eppig, {J. T.} and McAndrews, {M. S.} and A. Singer and Postlethwait, {J. H.}",
year = "2015",
month = nov,
doi = "10.1016/j.tig.2015.09.002",
language = "English",
volume = "31",
pages = "613--626",
journal = "Trends in Genetics",
issn = "0168-9525",
publisher = "ELSEVIER SCIENCE LONDON",
number = "11",

}

RIS

TY - JOUR

T1 - miRNA Nomenclature

T2 - A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants

AU - Desvignes, T.

AU - Batzel, P.

AU - Berezikov, E.

AU - Eilbeck, K.

AU - Eppig, J. T.

AU - McAndrews, M. S.

AU - Singer, A.

AU - Postlethwait, J. H.

PY - 2015/11

Y1 - 2015/11

N2 - High-throughput sequencing of miRNAs has revealed the diversity and variability of mature and functional short noncoding RNAs, including their genomic origins, biogenesis pathways, sequence variability, and newly identified products such as miRNA-offset RNAs (moRs). Here we review known cases of alternative mature miRNA-like RNA fragments and propose a revised definition of miRNAs to encompass this diversity. We then review nomenclature guidelines for miRNAs and propose to extend nomenclature conventions to align with those for protein-coding genes established by international consortia. Finally, we suggest a system to encompass the full complexity of sequence variations (i.e., isomiRs) in the analysis of small RNA sequencing experiments.

AB - High-throughput sequencing of miRNAs has revealed the diversity and variability of mature and functional short noncoding RNAs, including their genomic origins, biogenesis pathways, sequence variability, and newly identified products such as miRNA-offset RNAs (moRs). Here we review known cases of alternative mature miRNA-like RNA fragments and propose a revised definition of miRNAs to encompass this diversity. We then review nomenclature guidelines for miRNAs and propose to extend nomenclature conventions to align with those for protein-coding genes established by international consortia. Finally, we suggest a system to encompass the full complexity of sequence variations (i.e., isomiRs) in the analysis of small RNA sequencing experiments.

KW - PIWI-INTERACTING RNAS

KW - MICRORNA-OFFSET RNAS

KW - ANIMAL MICRORNAS

KW - REGULATORY RNAS

KW - NONCODING RNAS

KW - STEM-CELLS

KW - Y RNAS

KW - BIOGENESIS

KW - EVOLUTION

KW - ANNOTATION

U2 - 10.1016/j.tig.2015.09.002

DO - 10.1016/j.tig.2015.09.002

M3 - Review article

VL - 31

SP - 613

EP - 626

JO - Trends in Genetics

JF - Trends in Genetics

SN - 0168-9525

IS - 11

ER -

ID: 28859804