Microbiology of destructive periodontal disease in adolescent patients with congenital neutropenia - A report of 3 casesvan Winkelhoff, AJ., Schouten-van Meeteren, AYN., Baart, JA. & Vandenbroucke-Grauls, CMJE., Nov-2000, In : Journal of Clinical Periodontology. 27, 11, p. 793-798 6 p.
Research output: Contribution to journal › Article › Academic › peer-review
Background, aims: Congenital neutropenia is one condition that may predispose for destructive periodontal disease at a young age. In this report, we describe the microbiology of 3 adolescent patients with congenital neutropenia two of whom suffered from severe periodontitis.
Method: Microbiological testing of the parents was also performed in 1 case. DNA fingerprinting was used to study transmission of putative periodontal pathogens in this case. From 1 patient with periodontitis, Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis were isolated; a 2nd periodontitis patient was infected with P. gingivalis. A 3rd patient had gingivitis only and no A. actinomycetemcomitans or P. gingivalis were found.
Results: Using the amplified fragment length polymorphism DNA fingerprinting technique, bacterial transmission between the father and a patient was shown for A. actinomycetemcomitans but not for P. gingivalis.
|Number of pages||6|
|Journal||Journal of Clinical Periodontology|
|Publication status||Published - Nov-2000|
- periodontitis, neutropenia, microbiology, ACTINOMYCETEMCOMITANS-ASSOCIATED PERIODONTITIS, PREPUBERTAL PERIODONTITIS, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PORPHYROMONAS-GINGIVALIS, METRONIDAZOLE, CHILDREN, FAMILY