Publication

Microbial dehalogenation

Janssen, DB., Oppentocht, JE. & Poelarends, GJ., Jun-2001, In : Current Opinion in Biotechnology. 12, 3, p. 254-258 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Copy link to clipboard

Documents

DOI

Novel dehalogenases have been identified recently in various bacteria that utilise halogenated substrates. X-ray studies and sequence analysis have revealed insight into the molecular mechanisms of hydrolytic dehalogenases. Furthermore, genetic and biochemical studies have indicated that reductive dehalogenases are extra-cytoplasmic corrinoid-containing iron-sulphur proteins. Sequence analysis and mutagenesis studies indicate that several dehalogenases are homologous to enzymes that carry out transformations on non-halogenated substrates.

Original languageEnglish
Pages (from-to)254-258
Number of pages5
JournalCurrent Opinion in Biotechnology
Volume12
Issue number3
Publication statusPublished - Jun-2001

    Keywords

  • SPHINGOMONAS-PAUCIMOBILIS UT26, DESULFITOBACTERIUM DEHALOGENANS, L-2-HALOACID DEHALOGENASE, HALOALKANE DEHALOGENASE, REDUCTIVE DEHALOGENASE, CRYSTAL-STRUCTURES, ENZYME, GENE, DEGRADATION, SP.

Download statistics

No data available

ID: 3945504