Microbial dehalogenationJanssen, DB., Oppentocht, JE. & Poelarends, GJ., Jun-2001, In : Current Opinion in Biotechnology. 12, 3, p. 254-258 5 p.
Research output: Contribution to journal › Review article › Academic › peer-review
Novel dehalogenases have been identified recently in various bacteria that utilise halogenated substrates. X-ray studies and sequence analysis have revealed insight into the molecular mechanisms of hydrolytic dehalogenases. Furthermore, genetic and biochemical studies have indicated that reductive dehalogenases are extra-cytoplasmic corrinoid-containing iron-sulphur proteins. Sequence analysis and mutagenesis studies indicate that several dehalogenases are homologous to enzymes that carry out transformations on non-halogenated substrates.
|Number of pages||5|
|Journal||Current Opinion in Biotechnology|
|Publication status||Published - Jun-2001|
- SPHINGOMONAS-PAUCIMOBILIS UT26, DESULFITOBACTERIUM DEHALOGENANS, L-2-HALOACID DEHALOGENASE, HALOALKANE DEHALOGENASE, REDUCTIVE DEHALOGENASE, CRYSTAL-STRUCTURES, ENZYME, GENE, DEGRADATION, SP.