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Microbial Characteristics of Peri-Implantitis: A Case-Control Study

de Waal, Y. C. M., Eijsbouts, H. V. L. C., Winkel, E. G. & van Winkelhoff, A. J., Feb-2017, In : Journal of Periodontology. 88, 2, p. 209-217 9 p.

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  • Microbial Characteristics of Peri-Implantitis

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DOI

BACKGROUND: Aim of this case-control study was to compare oral microbiological characteristics of subjects with healthy peri-implant conditions and subjects with peri-implantitis and to explore the influence of various patient-related and implant-related factors on the microbiological characteristics.

METHODS: Peri-implant submucosal microbial samples were collected from 85 patients with peri-implantitis (cases) and from 69 patients with only implants with healthy peri-implant conditions (controls). Samples were analyzed using culturing techniques. Multivariable logistic regression was used to explore the association of disease status and various patient- and implant-related factors (gender, patient age, smoking, number of remaining teeth, percentage of teeth with bone loss, implant function time, implant surface and presence of plaque) with microbiological characteristics.

RESULTS: Peri-implant disease status was significantly associated with the submucosal presence of P. gingivalis, P. intermedia, T. forsythia, and F. nucleatum. The association with disease status was most obvious for P. intermedia (OR 15.1, 95% CI [5.1, 45.3]) and T. forsythia (OR 13.3, 95% CI [5.4, 32.5]). The prevalence of A. actinomycetemcomitans and Staphylococcus species was very low.

CONCLUSIONS: The periodontal pathogens P. gingivalis, P. intermedia, T. forsythia and F. nucleatum are associated with peri-implantitis. A. actinomycetemcomitans and Staphylococcus species do not seem to play an important role in peri-implantitis.

Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalJournal of Periodontology
Volume88
Issue number2
Early online date26-Sep-2016
Publication statusPublished - Feb-2017

    Keywords

  • Bacteria, case-control studies, dental implants, infection, microbiology, periodontal diseases, PARTIALLY EDENTULOUS PATIENTS, MOUTH TOOTH EXTRACTION, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PERIODONTAL PATHOGENS, ANAEROBIC CULTURE, CONTROLLED-TRIAL, TRANSPORT MEDIA, ADJACENT TEETH, HOST RESPONSE, DOUBLE-BLIND

ID: 35870740