Mechanisms of enhanced thrombin generating capacity in patients with cirrhosis.Lisman, J., Bos, S. & Intagliata, N. M., Jun-2018, In : JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 16, 6, p. 1128-1131 4 p.
Research output: Contribution to journal › Article › Academic › peer-review
The liver is the site of synthesis of many proteins involved in hemostasis including pro- and anticoagulant proteins, pro- and antifibrinolytic proteins, and thrombopoietin. Consequently, patients with liver disease acquire complex changes within their hemostatic system. Historically, these changes were thought to result in a bleeding diathesis. Although bleeding complications are common in patients with chronic liver disease, the most common bleeding complication, variceal bleeding, is a consequence of portal hypertension, rather than hemostatic failure.
|Number of pages||4|
|Journal||JOURNAL OF THROMBOSIS AND HAEMOSTASIS|
|Publication status||Published - Jun-2018|
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