Publication

Mechanical valves in the pulmonary position: An international retrospective analysis

Pragt, H., van Melle, J. P., Javadikasgari, H., Seo, D. M., Stulak, J. M., Knez, I., Hoerer, J., Munoz-Guijosa, C., Dehaki, M. G., Shin, H. J., Dearani, J. A., Dehaki, M. G., Pieper, P. G., Eulenburg, C., Dos, L. & Ebels, T., Oct-2017, In : JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 154, 4, p. 1371-1378.e1 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Pragt, H., van Melle, J. P., Javadikasgari, H., Seo, D. M., Stulak, J. M., Knez, I., ... Ebels, T. (2017). Mechanical valves in the pulmonary position: An international retrospective analysis. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 154(4), 1371-1378.e1. https://doi.org/10.1016/j.jtcvs.2017.04.072

Author

Pragt, Hanna ; van Melle, Joost P. ; Javadikasgari, Hoda ; Seo, Dong Man ; Stulak, John M. ; Knez, Igor ; Hoerer, Juergen ; Munoz-Guijosa, Christian ; Dehaki, Mahyar G. ; Shin, Hong Ju ; Dearani, Joseph A. ; Dehaki, Maziar G. ; Pieper, Petronella G. ; Eulenburg, Christine ; Dos, Laura ; Ebels, Tjark. / Mechanical valves in the pulmonary position : An international retrospective analysis. In: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2017 ; Vol. 154, No. 4. pp. 1371-1378.e1.

Harvard

Pragt, H, van Melle, JP, Javadikasgari, H, Seo, DM, Stulak, JM, Knez, I, Hoerer, J, Munoz-Guijosa, C, Dehaki, MG, Shin, HJ, Dearani, JA, Dehaki, MG, Pieper, PG, Eulenburg, C, Dos, L & Ebels, T 2017, 'Mechanical valves in the pulmonary position: An international retrospective analysis', JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol. 154, no. 4, pp. 1371-1378.e1. https://doi.org/10.1016/j.jtcvs.2017.04.072

Standard

Mechanical valves in the pulmonary position : An international retrospective analysis. / Pragt, Hanna; van Melle, Joost P.; Javadikasgari, Hoda; Seo, Dong Man; Stulak, John M.; Knez, Igor; Hoerer, Juergen; Munoz-Guijosa, Christian; Dehaki, Mahyar G.; Shin, Hong Ju; Dearani, Joseph A.; Dehaki, Maziar G.; Pieper, Petronella G.; Eulenburg, Christine; Dos, Laura; Ebels, Tjark.

In: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol. 154, No. 4, 10.2017, p. 1371-1378.e1.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Pragt H, van Melle JP, Javadikasgari H, Seo DM, Stulak JM, Knez I et al. Mechanical valves in the pulmonary position: An international retrospective analysis. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2017 Oct;154(4):1371-1378.e1. https://doi.org/10.1016/j.jtcvs.2017.04.072


BibTeX

@article{59568c9e73434f0db4443e09a300abbf,
title = "Mechanical valves in the pulmonary position: An international retrospective analysis",
abstract = "Objective: Life expectancy of patients with congenital heart disease has improved over the past decades, increasing the need for a durable pulmonary prosthetic valve. Biological valves in various forms have become the valve of choice for pulmonary valve replacement (PVR), but structural valve deterioration is unavoidable in the long term. Use of a mechanical valve could be an alternative, but data on long-term outcomes are sparse.Methods: We retrospectively collected and analyzed data on 364 patients with mechanical valves implanted in the pulmonary position between 1965 and 2014. The data originate from medical centers in Barcelona (Spain), Graz (Austria), Groningen (the Netherlands), Munich (Germany), Rochester (United States), Seoul (Republic of Korea), and Tehran (Iran).Results: Median follow-up duration was 4.26 years (range, 0-27 years), mean age at implantation was 27.16 +/- 12.2 years. Tetralogy of Fallot was the most common primary cardiac diagnosis, with a subgroup of 69.8{\%}. Freedom from valvular thrombosis was 91{\%} (95{\%} confidence interval [CI], 87{\%}-94{\%}) at 5 years and 86{\%} (95{\%} CI, 81{\%}-91{\%}) at 10 years post-PVR. With a success rate up to 88{\%}, thrombolysis was a successful therapy. Freedom from reoperation was 97{\%} (95{\%} CI, 94{\%}-99{\%}) at 5 years post-PVR and 91{\%} (95{\%} CI, 85{\%}95{\%}) at 10 years.Conclusions: Mechanical PVR is associated with a limited risk of valvular thrombosis. Thrombolysis was an effective treatment in the majority.",
keywords = "congenital heart disease, mechanical heart valve pulmonary valve replacement, CONGENITAL HEART-DISEASE, TERM-FOLLOW-UP, INFECTIVE ENDOCARDITIS, 20-YEAR EXPERIENCE, REPLACEMENT, PROSTHESES, OUTCOMES, CARBOMEDICS, FALLOT, PERFORMANCE",
author = "Hanna Pragt and {van Melle}, {Joost P.} and Hoda Javadikasgari and Seo, {Dong Man} and Stulak, {John M.} and Igor Knez and Juergen Hoerer and Christian Munoz-Guijosa and Dehaki, {Mahyar G.} and Shin, {Hong Ju} and Dearani, {Joseph A.} and Dehaki, {Maziar G.} and Pieper, {Petronella G.} and Christine Eulenburg and Laura Dos and Tjark Ebels",
year = "2017",
month = "10",
doi = "10.1016/j.jtcvs.2017.04.072",
language = "English",
volume = "154",
pages = "1371--1378.e1",
journal = "JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY",
issn = "0022-5223",
publisher = "MOSBY-ELSEVIER",
number = "4",

}

RIS

TY - JOUR

T1 - Mechanical valves in the pulmonary position

T2 - An international retrospective analysis

AU - Pragt, Hanna

AU - van Melle, Joost P.

AU - Javadikasgari, Hoda

AU - Seo, Dong Man

AU - Stulak, John M.

AU - Knez, Igor

AU - Hoerer, Juergen

AU - Munoz-Guijosa, Christian

AU - Dehaki, Mahyar G.

AU - Shin, Hong Ju

AU - Dearani, Joseph A.

AU - Dehaki, Maziar G.

AU - Pieper, Petronella G.

AU - Eulenburg, Christine

AU - Dos, Laura

AU - Ebels, Tjark

PY - 2017/10

Y1 - 2017/10

N2 - Objective: Life expectancy of patients with congenital heart disease has improved over the past decades, increasing the need for a durable pulmonary prosthetic valve. Biological valves in various forms have become the valve of choice for pulmonary valve replacement (PVR), but structural valve deterioration is unavoidable in the long term. Use of a mechanical valve could be an alternative, but data on long-term outcomes are sparse.Methods: We retrospectively collected and analyzed data on 364 patients with mechanical valves implanted in the pulmonary position between 1965 and 2014. The data originate from medical centers in Barcelona (Spain), Graz (Austria), Groningen (the Netherlands), Munich (Germany), Rochester (United States), Seoul (Republic of Korea), and Tehran (Iran).Results: Median follow-up duration was 4.26 years (range, 0-27 years), mean age at implantation was 27.16 +/- 12.2 years. Tetralogy of Fallot was the most common primary cardiac diagnosis, with a subgroup of 69.8%. Freedom from valvular thrombosis was 91% (95% confidence interval [CI], 87%-94%) at 5 years and 86% (95% CI, 81%-91%) at 10 years post-PVR. With a success rate up to 88%, thrombolysis was a successful therapy. Freedom from reoperation was 97% (95% CI, 94%-99%) at 5 years post-PVR and 91% (95% CI, 85%95%) at 10 years.Conclusions: Mechanical PVR is associated with a limited risk of valvular thrombosis. Thrombolysis was an effective treatment in the majority.

AB - Objective: Life expectancy of patients with congenital heart disease has improved over the past decades, increasing the need for a durable pulmonary prosthetic valve. Biological valves in various forms have become the valve of choice for pulmonary valve replacement (PVR), but structural valve deterioration is unavoidable in the long term. Use of a mechanical valve could be an alternative, but data on long-term outcomes are sparse.Methods: We retrospectively collected and analyzed data on 364 patients with mechanical valves implanted in the pulmonary position between 1965 and 2014. The data originate from medical centers in Barcelona (Spain), Graz (Austria), Groningen (the Netherlands), Munich (Germany), Rochester (United States), Seoul (Republic of Korea), and Tehran (Iran).Results: Median follow-up duration was 4.26 years (range, 0-27 years), mean age at implantation was 27.16 +/- 12.2 years. Tetralogy of Fallot was the most common primary cardiac diagnosis, with a subgroup of 69.8%. Freedom from valvular thrombosis was 91% (95% confidence interval [CI], 87%-94%) at 5 years and 86% (95% CI, 81%-91%) at 10 years post-PVR. With a success rate up to 88%, thrombolysis was a successful therapy. Freedom from reoperation was 97% (95% CI, 94%-99%) at 5 years post-PVR and 91% (95% CI, 85%95%) at 10 years.Conclusions: Mechanical PVR is associated with a limited risk of valvular thrombosis. Thrombolysis was an effective treatment in the majority.

KW - congenital heart disease

KW - mechanical heart valve pulmonary valve replacement

KW - CONGENITAL HEART-DISEASE

KW - TERM-FOLLOW-UP

KW - INFECTIVE ENDOCARDITIS

KW - 20-YEAR EXPERIENCE

KW - REPLACEMENT

KW - PROSTHESES

KW - OUTCOMES

KW - CARBOMEDICS

KW - FALLOT

KW - PERFORMANCE

U2 - 10.1016/j.jtcvs.2017.04.072

DO - 10.1016/j.jtcvs.2017.04.072

M3 - Article

VL - 154

SP - 1371-1378.e1

JO - JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

JF - JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

SN - 0022-5223

IS - 4

ER -

ID: 49428381