Means and methods for sustained oxygen release in situ

Bulstra, S. K., Steg, H., Veldhuizen, A. G. & Kuijer, R., 9-Mar-2017, Patent No. WO2017039435, Priority date 28-Aug-2015

Research output: PatentProfessional

The invention relates to the field of tissue engineering and cell-based therapy. More in particular, it relates to an oxygen-releasing biomaterial that can enhance and support cell survival in vivo. Provided is an oxygen-delivering microsphere based on a biocompatible polymer, the microsphere comprising an agent capable of generating oxygen in situ encapsulated in a polymer matrix comprising poly (1,3-trimethylene carbonate) (PTMC). Also provided is an implantable device, like a scaffold for tissue engineering, comprising a plurality of oxygen-delivering microparticles according to the invention.
Original languageEnglish
Patent numberWO2017039435
Priority date28/08/2015
Publication statusPublished - 9-Mar-2017

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