Publication

Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture

van Pijkeren, A., Bischoff, R. & Kwiatkowski, M., 7-Dec-2019, In : Analyst. 144, 23, p. 6812-6833 22 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

van Pijkeren, A., Bischoff, R., & Kwiatkowski, M. (2019). Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture. Analyst, 144(23), 6812-6833. https://doi.org/10.1039/c9an01258c

Author

van Pijkeren, Alienke ; Bischoff, Rainer ; Kwiatkowski, Marcel. / Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture. In: Analyst. 2019 ; Vol. 144, No. 23. pp. 6812-6833.

Harvard

van Pijkeren, A, Bischoff, R & Kwiatkowski, M 2019, 'Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture', Analyst, vol. 144, no. 23, pp. 6812-6833. https://doi.org/10.1039/c9an01258c

Standard

Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture. / van Pijkeren, Alienke; Bischoff, Rainer; Kwiatkowski, Marcel.

In: Analyst, Vol. 144, No. 23, 07.12.2019, p. 6812-6833.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

van Pijkeren A, Bischoff R, Kwiatkowski M. Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture. Analyst. 2019 Dec 7;144(23):6812-6833. https://doi.org/10.1039/c9an01258c


BibTeX

@article{d84ebcfffa0d4d1e9be9ef11bc655036,
title = "Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture",
abstract = "Biological organisms represent highly dynamic systems, which are continually exposed to environmental factors and always strive to restore steady-state homeostasis. Posttranslational modifications are key regulators with which biological systems respond to external stimuli. To understand how homeostasis is restored, it is important to study the kinetics of posttranslational modifications. In this review we discuss proteomic approaches using stable isotope labeled metabolic precursors to study dynamics of posttranslational modifications in cell culture.",
keywords = "ACETYL-COA SYNTHETASE, ULTRAVIOLET-LASER DESORPTION, O-GLCNAC TRANSFERASE, QUANTIFYING IN-VIVO, LYSINE ACETYLATION, HISTONE ACETYLATION, ARGININE DIMETHYLATION, PROTEOLYTIC CLEAVAGE, PROTEIN METHYLATION, HIGH-SENSITIVITY",
author = "{van Pijkeren}, Alienke and Rainer Bischoff and Marcel Kwiatkowski",
year = "2019",
month = "12",
day = "7",
doi = "10.1039/c9an01258c",
language = "English",
volume = "144",
pages = "6812--6833",
journal = "Analyst",
issn = "0003-2654",
number = "23",

}

RIS

TY - JOUR

T1 - Mass spectrometric analysis of PTM dynamics using stable isotope labeled metabolic precursors in cell culture

AU - van Pijkeren, Alienke

AU - Bischoff, Rainer

AU - Kwiatkowski, Marcel

PY - 2019/12/7

Y1 - 2019/12/7

N2 - Biological organisms represent highly dynamic systems, which are continually exposed to environmental factors and always strive to restore steady-state homeostasis. Posttranslational modifications are key regulators with which biological systems respond to external stimuli. To understand how homeostasis is restored, it is important to study the kinetics of posttranslational modifications. In this review we discuss proteomic approaches using stable isotope labeled metabolic precursors to study dynamics of posttranslational modifications in cell culture.

AB - Biological organisms represent highly dynamic systems, which are continually exposed to environmental factors and always strive to restore steady-state homeostasis. Posttranslational modifications are key regulators with which biological systems respond to external stimuli. To understand how homeostasis is restored, it is important to study the kinetics of posttranslational modifications. In this review we discuss proteomic approaches using stable isotope labeled metabolic precursors to study dynamics of posttranslational modifications in cell culture.

KW - ACETYL-COA SYNTHETASE

KW - ULTRAVIOLET-LASER DESORPTION

KW - O-GLCNAC TRANSFERASE

KW - QUANTIFYING IN-VIVO

KW - LYSINE ACETYLATION

KW - HISTONE ACETYLATION

KW - ARGININE DIMETHYLATION

KW - PROTEOLYTIC CLEAVAGE

KW - PROTEIN METHYLATION

KW - HIGH-SENSITIVITY

U2 - 10.1039/c9an01258c

DO - 10.1039/c9an01258c

M3 - Review article

VL - 144

SP - 6812

EP - 6833

JO - Analyst

JF - Analyst

SN - 0003-2654

IS - 23

ER -

ID: 100490755