Publication

Manipulation of selective macroautophagy by pathogens at a glance

Cong, Y., Dinesh Kumar, N., Mauthe, M., Verlhac, P. & Reggiori, F., 2020, In : Journal of Cell Science. 133, 10, 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Cong, Y., Dinesh Kumar, N., Mauthe, M., Verlhac, P., & Reggiori, F. (2020). Manipulation of selective macroautophagy by pathogens at a glance. Journal of Cell Science, 133(10). https://doi.org/10.1242/jcs.240440

Author

Cong, Yingying ; Dinesh Kumar, Nilima ; Mauthe, Mario ; Verlhac, Pauline ; Reggiori, Fulvio. / Manipulation of selective macroautophagy by pathogens at a glance. In: Journal of Cell Science. 2020 ; Vol. 133, No. 10.

Harvard

Cong, Y, Dinesh Kumar, N, Mauthe, M, Verlhac, P & Reggiori, F 2020, 'Manipulation of selective macroautophagy by pathogens at a glance', Journal of Cell Science, vol. 133, no. 10. https://doi.org/10.1242/jcs.240440

Standard

Manipulation of selective macroautophagy by pathogens at a glance. / Cong, Yingying; Dinesh Kumar, Nilima; Mauthe, Mario; Verlhac, Pauline; Reggiori, Fulvio.

In: Journal of Cell Science, Vol. 133, No. 10, 2020.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Cong Y, Dinesh Kumar N, Mauthe M, Verlhac P, Reggiori F. Manipulation of selective macroautophagy by pathogens at a glance. Journal of Cell Science. 2020;133(10). https://doi.org/10.1242/jcs.240440


BibTeX

@article{24e99c023d9444e8b445cc9df3850c28,
title = "Manipulation of selective macroautophagy by pathogens at a glance",
abstract = "Macroautophagy (hereafter autophagy) is a highly conserved catabolic pathway, which mediates the delivery of unwanted cytoplasmic structures and organelles to lysosomes for degradation. In numerous situations, autophagy is highly selective and exclusively targets specific intracellular components. Selective types of autophagy are a central element of our cell-autonomous innate immunity as they can mediate the turnover of viruses or bacteria, that gain access to the cytoplasm of the cell. Selective autophagy also modulates other aspects of our immunity by turning over specific immunoregulators. Throughout evolution, however, the continuous interaction between this fundamental cellular pathway and pathogens has led several pathogens to develop exquisite mechanisms to inhibit or subvert selective types of autophagy, to promote their intracellular multiplication. This Cell Science at a Glance article and the accompanying poster provides an overview of the selective autophagy of both pathogens, known as xenophagy, and of immunoregulators, and highlights a few archetypal examples that illustrate molecular strategies developed by viruses and bacteria to manipulate selective autophagy for their own benefit.",
author = "Yingying Cong and {Dinesh Kumar}, Nilima and Mario Mauthe and Pauline Verlhac and Fulvio Reggiori",
note = "{\circledC} 2020. Published by The Company of Biologists Ltd.",
year = "2020",
doi = "10.1242/jcs.240440",
language = "English",
volume = "133",
journal = "Journal of Cell Science",
issn = "0021-9533",
publisher = "COMPANY OF BIOLOGISTS LTD",
number = "10",

}

RIS

TY - JOUR

T1 - Manipulation of selective macroautophagy by pathogens at a glance

AU - Cong, Yingying

AU - Dinesh Kumar, Nilima

AU - Mauthe, Mario

AU - Verlhac, Pauline

AU - Reggiori, Fulvio

N1 - © 2020. Published by The Company of Biologists Ltd.

PY - 2020

Y1 - 2020

N2 - Macroautophagy (hereafter autophagy) is a highly conserved catabolic pathway, which mediates the delivery of unwanted cytoplasmic structures and organelles to lysosomes for degradation. In numerous situations, autophagy is highly selective and exclusively targets specific intracellular components. Selective types of autophagy are a central element of our cell-autonomous innate immunity as they can mediate the turnover of viruses or bacteria, that gain access to the cytoplasm of the cell. Selective autophagy also modulates other aspects of our immunity by turning over specific immunoregulators. Throughout evolution, however, the continuous interaction between this fundamental cellular pathway and pathogens has led several pathogens to develop exquisite mechanisms to inhibit or subvert selective types of autophagy, to promote their intracellular multiplication. This Cell Science at a Glance article and the accompanying poster provides an overview of the selective autophagy of both pathogens, known as xenophagy, and of immunoregulators, and highlights a few archetypal examples that illustrate molecular strategies developed by viruses and bacteria to manipulate selective autophagy for their own benefit.

AB - Macroautophagy (hereafter autophagy) is a highly conserved catabolic pathway, which mediates the delivery of unwanted cytoplasmic structures and organelles to lysosomes for degradation. In numerous situations, autophagy is highly selective and exclusively targets specific intracellular components. Selective types of autophagy are a central element of our cell-autonomous innate immunity as they can mediate the turnover of viruses or bacteria, that gain access to the cytoplasm of the cell. Selective autophagy also modulates other aspects of our immunity by turning over specific immunoregulators. Throughout evolution, however, the continuous interaction between this fundamental cellular pathway and pathogens has led several pathogens to develop exquisite mechanisms to inhibit or subvert selective types of autophagy, to promote their intracellular multiplication. This Cell Science at a Glance article and the accompanying poster provides an overview of the selective autophagy of both pathogens, known as xenophagy, and of immunoregulators, and highlights a few archetypal examples that illustrate molecular strategies developed by viruses and bacteria to manipulate selective autophagy for their own benefit.

U2 - 10.1242/jcs.240440

DO - 10.1242/jcs.240440

M3 - Review article

C2 - 32461337

VL - 133

JO - Journal of Cell Science

JF - Journal of Cell Science

SN - 0021-9533

IS - 10

ER -

ID: 126737596