Publication

Local excision and mucosal advancement for anorectal ulceration in patients infected with human-immunodeficiency-virus

CONSTEN, ECJ., SLORS, JFM., DANNER, SA., OFFERHAUS, GJA., BARTELSMAN, JFWM. & VANLANSCHOT, JJB., Jul-1995, In : British Journal of Surgery. 82, 7, p. 891-894 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Copy link to clipboard

Documents

  • Local excision and mucosal advancement for anorectal ulceration in patients infected with human immunodeficiency virus

    Final publisher's version, 454 KB, PDF document

    Request copy

DOI

  • ECJ CONSTEN
  • JFM SLORS
  • SA DANNER
  • GJA OFFERHAUS
  • JFWM BARTELSMAN
  • JJB VANLANSCHOT

In patients infected with human immunodeficiency virus (HIV) no effective surgical procedure has been described for anorectal ulceration that is resistant to medical therapy. This study was designed to determine the effectiveness of surgical excision of anorectal ulcers, with or without mucosal advancement. The medical records of patients with HIV and anorectal pathology diagnosed between 1984 and 1994 were reviewed. Patients with anorectal ulcers were divided into group A which was treated only with excision and group B in which excision was combined with mucosal advancement. Surgical treatment was considered successful if relief of symptoms was achieved within 4 weeks of the operation. Excision of anorectal ulcers was successful in seven of 16 patients (44 per cent) in group A. Relief of symptoms was achieved in 12 of 13 patients (92 per cent) in group B when surgical excision was combined with mucosal advancement, which is significantly better than the results in group A (P=0.02). This non-randomized study indicates that after unsuccessful medical treatment persistent symptomatic ulcers should be treated operatively by excision with mucosal advancement.

Original languageEnglish
Pages (from-to)891-894
Number of pages4
JournalBritish Journal of Surgery
Volume82
Issue number7
Publication statusPublished - Jul-1995
Externally publishedYes

    Keywords

  • HIV-INFECTION, SURGICAL-MANAGEMENT, SURGERY, HOMOSEXUALS, DISEASES, AIDS

ID: 136498123