Publication

Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period

van der Reijden, W. A., Bosch-Tijhof, C. J., van der Velden, U. & van Winkelhoff, A. J., Jun-2008, In : Journal of Clinical Periodontology. 35, 6, p. 487-492 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

van der Reijden, W. A., Bosch-Tijhof, C. J., van der Velden, U., & van Winkelhoff, A. J. (2008). Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period. Journal of Clinical Periodontology, 35(6), 487-492. https://doi.org/10.1111/j.1600-051X.2008.01218.x

Author

van der Reijden, Wil A. ; Bosch-Tijhof, Carolien J. ; van der Velden, Ubele ; van Winkelhoff, Arie Jan. / Java project on periodontal diseases : serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period. In: Journal of Clinical Periodontology. 2008 ; Vol. 35, No. 6. pp. 487-492.

Harvard

van der Reijden, WA, Bosch-Tijhof, CJ, van der Velden, U & van Winkelhoff, AJ 2008, 'Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period', Journal of Clinical Periodontology, vol. 35, no. 6, pp. 487-492. https://doi.org/10.1111/j.1600-051X.2008.01218.x

Standard

Java project on periodontal diseases : serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period. / van der Reijden, Wil A.; Bosch-Tijhof, Carolien J.; van der Velden, Ubele; van Winkelhoff, Arie Jan.

In: Journal of Clinical Periodontology, Vol. 35, No. 6, 06.2008, p. 487-492.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

van der Reijden WA, Bosch-Tijhof CJ, van der Velden U, van Winkelhoff AJ. Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period. Journal of Clinical Periodontology. 2008 Jun;35(6):487-492. https://doi.org/10.1111/j.1600-051X.2008.01218.x


BibTeX

@article{94607cb6d1114729b980e8144a6e680b,
title = "Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period",
abstract = "Objective: To investigate the serotype distribution and stability of Aggregatibacter actinomycetemcomitans over an 8-year period in untreated Indonesian subjects.Material and Methods: Clinical periodontal status and the presence of A. actinomycetemcomitans were established in 1994 and 2002 in 107 subjects from an Indonesian tea estate deprived from dental care. On an average, 3.6 isolates per patient were subcultured and serotyped using specific PCR reactions.Results: In 1994, the predominant serotype was b (53.7{\%}), whereas a and c occurred in 17.1{\%} and 14.6{\%} of the subjects, respectively. In 2002, a reduction in serotypes a (7.5{\%}) and b (30.2{\%}) occurred. Serotypes c and e increased in prevalence from 14.6{\%} to 35.8{\%} and 2.4{\%} to 9.4{\%}, respectively. Multiple serotypes were found in 12.2{\%} in 1994 and 17{\%} in 2002. From 24 subjects who were positive at both time points, 14 (58.3{\%}) had the same serotype, whereas in 10 subjects (41.7{\%}), a different serotype was found. Mean clinical attachment loss had increased from 0.74 mm in 1994 to 1.96 mm in 2002 but could not be related to subgingival presence of A. actinomycetemcomitans.Conclusions: A. actinomycetemcomitans serotypes distribution in Indonesian young adults shifts from predominantly serotype b to a more equal prevalence of serotypes b and c. This shift suggests an opportunistic character of A. actinomycetemcomitans.",
keywords = "A. actinomycetemcomitans, periodontitis, serotyping, LOCALIZED JUVENILE PERIODONTITIS, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PORPHYROMONAS-GINGIVALIS, AGGRESSIVE PERIODONTITIS, SERUM ANTIBODY, ADOLESCENTS, POPULATION, FREQUENCY, ACQUISITION, STABILITY",
author = "{van der Reijden}, {Wil A.} and Bosch-Tijhof, {Carolien J.} and {van der Velden}, Ubele and {van Winkelhoff}, {Arie Jan}",
year = "2008",
month = "6",
doi = "10.1111/j.1600-051X.2008.01218.x",
language = "English",
volume = "35",
pages = "487--492",
journal = "Journal of Clinical Periodontology",
issn = "0303-6979",
publisher = "Wiley",
number = "6",

}

RIS

TY - JOUR

T1 - Java project on periodontal diseases

T2 - serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period

AU - van der Reijden, Wil A.

AU - Bosch-Tijhof, Carolien J.

AU - van der Velden, Ubele

AU - van Winkelhoff, Arie Jan

PY - 2008/6

Y1 - 2008/6

N2 - Objective: To investigate the serotype distribution and stability of Aggregatibacter actinomycetemcomitans over an 8-year period in untreated Indonesian subjects.Material and Methods: Clinical periodontal status and the presence of A. actinomycetemcomitans were established in 1994 and 2002 in 107 subjects from an Indonesian tea estate deprived from dental care. On an average, 3.6 isolates per patient were subcultured and serotyped using specific PCR reactions.Results: In 1994, the predominant serotype was b (53.7%), whereas a and c occurred in 17.1% and 14.6% of the subjects, respectively. In 2002, a reduction in serotypes a (7.5%) and b (30.2%) occurred. Serotypes c and e increased in prevalence from 14.6% to 35.8% and 2.4% to 9.4%, respectively. Multiple serotypes were found in 12.2% in 1994 and 17% in 2002. From 24 subjects who were positive at both time points, 14 (58.3%) had the same serotype, whereas in 10 subjects (41.7%), a different serotype was found. Mean clinical attachment loss had increased from 0.74 mm in 1994 to 1.96 mm in 2002 but could not be related to subgingival presence of A. actinomycetemcomitans.Conclusions: A. actinomycetemcomitans serotypes distribution in Indonesian young adults shifts from predominantly serotype b to a more equal prevalence of serotypes b and c. This shift suggests an opportunistic character of A. actinomycetemcomitans.

AB - Objective: To investigate the serotype distribution and stability of Aggregatibacter actinomycetemcomitans over an 8-year period in untreated Indonesian subjects.Material and Methods: Clinical periodontal status and the presence of A. actinomycetemcomitans were established in 1994 and 2002 in 107 subjects from an Indonesian tea estate deprived from dental care. On an average, 3.6 isolates per patient were subcultured and serotyped using specific PCR reactions.Results: In 1994, the predominant serotype was b (53.7%), whereas a and c occurred in 17.1% and 14.6% of the subjects, respectively. In 2002, a reduction in serotypes a (7.5%) and b (30.2%) occurred. Serotypes c and e increased in prevalence from 14.6% to 35.8% and 2.4% to 9.4%, respectively. Multiple serotypes were found in 12.2% in 1994 and 17% in 2002. From 24 subjects who were positive at both time points, 14 (58.3%) had the same serotype, whereas in 10 subjects (41.7%), a different serotype was found. Mean clinical attachment loss had increased from 0.74 mm in 1994 to 1.96 mm in 2002 but could not be related to subgingival presence of A. actinomycetemcomitans.Conclusions: A. actinomycetemcomitans serotypes distribution in Indonesian young adults shifts from predominantly serotype b to a more equal prevalence of serotypes b and c. This shift suggests an opportunistic character of A. actinomycetemcomitans.

KW - A. actinomycetemcomitans

KW - periodontitis

KW - serotyping

KW - LOCALIZED JUVENILE PERIODONTITIS

KW - ACTINOBACILLUS-ACTINOMYCETEMCOMITANS

KW - PORPHYROMONAS-GINGIVALIS

KW - AGGRESSIVE PERIODONTITIS

KW - SERUM ANTIBODY

KW - ADOLESCENTS

KW - POPULATION

KW - FREQUENCY

KW - ACQUISITION

KW - STABILITY

U2 - 10.1111/j.1600-051X.2008.01218.x

DO - 10.1111/j.1600-051X.2008.01218.x

M3 - Article

C2 - 18422698

VL - 35

SP - 487

EP - 492

JO - Journal of Clinical Periodontology

JF - Journal of Clinical Periodontology

SN - 0303-6979

IS - 6

ER -

ID: 13926468