Isolation of two cytotoxic diterpenes from the fern Pteris multifida

Woerdenbag, HJ., Lutke, LR., Bos, R., Stevens, JF., Hulst, R., Kruizinga, WH., Elema, ET., Hendriks, H., vanUden, W. & Pras, N., 1996, In : Zeitschrift fur naturforschung c-A journal of biosciences. 51, 9-10, p. 635-638 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

From aerial parts of the fern Pteris multifida Poir. (Polypodiaceae) two diterpenes, ent-kaurane-2 beta,16 alpha-diol and ent-kaur-16-ene-2 beta,15 alpha-diol, were isolated by repeated column chromatography using silica gel and silica gel impregnated with silver nitrate. The structures were confirmed by spectroscopic methods. Both compounds showed a moderate cytotoxicity to Ehrlich ascites tumour cells.

Original languageEnglish
Pages (from-to)635-638
Number of pages4
JournalZeitschrift fur naturforschung c-A journal of biosciences
Issue number9-10
Publication statusPublished - 1996

ID: 6485086