Publication

Ischemia and left ventricular dysfunction: A reciprocal relation?

van Veldhuisen, DJ., van den Heuvel, AFM., Blanksma, PK. & Crijns, HJGM., 1998, In : Journal of Cardiovascular Pharmacology. 32, p. S46-S51 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

van Veldhuisen, DJ., van den Heuvel, AFM., Blanksma, PK., & Crijns, HJGM. (1998). Ischemia and left ventricular dysfunction: A reciprocal relation? Journal of Cardiovascular Pharmacology, 32, S46-S51.

Author

van Veldhuisen, DJ ; van den Heuvel, AFM ; Blanksma, PK ; Crijns, HJGM. / Ischemia and left ventricular dysfunction : A reciprocal relation?. In: Journal of Cardiovascular Pharmacology. 1998 ; Vol. 32. pp. S46-S51.

Harvard

van Veldhuisen, DJ, van den Heuvel, AFM, Blanksma, PK & Crijns, HJGM 1998, 'Ischemia and left ventricular dysfunction: A reciprocal relation?', Journal of Cardiovascular Pharmacology, vol. 32, pp. S46-S51.

Standard

Ischemia and left ventricular dysfunction : A reciprocal relation? / van Veldhuisen, DJ; van den Heuvel, AFM; Blanksma, PK; Crijns, HJGM.

In: Journal of Cardiovascular Pharmacology, Vol. 32, 1998, p. S46-S51.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

van Veldhuisen DJ, van den Heuvel AFM, Blanksma PK, Crijns HJGM. Ischemia and left ventricular dysfunction: A reciprocal relation? Journal of Cardiovascular Pharmacology. 1998;32:S46-S51.


BibTeX

@article{21f79b2c1b2c41acbf86fdc67e7d2c18,
title = "Ischemia and left ventricular dysfunction: A reciprocal relation?",
abstract = "There is convincing evidence that (prolonged) episodes of myocardial ischemia lead to impairment of left ventricular (LV) function and ultimately to chronic congestive hear? failure (CHF), but whether the opposite is also true has not been well established. We studied this issue in two groups of CHF patients with positron emission tomography (PET)by using [N-13]ammonia ((NH3)-N-13) as a tracer. In the first protocol we compared 12 patients with idiopathic dilated cardiomyopathy (who have normal coronary arteries) with 12 healthy controls, In the second protocol we studied a group of 24 patients with documented coronary artery disease (CAD). In this protocol, we compared patients with normal LV function to those with LV dysfunction and CHF. In patients with cardiomyopathy, myocardial blood flow at rest was normal but flow reserve (after dipyridamole infusion) was significantly impaired (1.7 +/- 0.08) compared with normal subjects (2.7 +/- 0.01; p",
keywords = "congestive heart failure, idiopathic dilated cardiomyopathy, ischemia, left ventricular function, metabolic studies, MYOCARDIAL BLOOD-FLOW, CHRONIC HEART-FAILURE, WALL-MOTION, METABOLISM, CARVEDILOL, TOMOGRAPHY, PERFUSION, ANGINA",
author = "{van Veldhuisen}, DJ and {van den Heuvel}, AFM and PK Blanksma and HJGM Crijns",
year = "1998",
language = "English",
volume = "32",
pages = "S46--S51",
journal = "Journal of Cardiovascular Pharmacology",
issn = "0160-2446",

}

RIS

TY - JOUR

T1 - Ischemia and left ventricular dysfunction

T2 - A reciprocal relation?

AU - van Veldhuisen, DJ

AU - van den Heuvel, AFM

AU - Blanksma, PK

AU - Crijns, HJGM

PY - 1998

Y1 - 1998

N2 - There is convincing evidence that (prolonged) episodes of myocardial ischemia lead to impairment of left ventricular (LV) function and ultimately to chronic congestive hear? failure (CHF), but whether the opposite is also true has not been well established. We studied this issue in two groups of CHF patients with positron emission tomography (PET)by using [N-13]ammonia ((NH3)-N-13) as a tracer. In the first protocol we compared 12 patients with idiopathic dilated cardiomyopathy (who have normal coronary arteries) with 12 healthy controls, In the second protocol we studied a group of 24 patients with documented coronary artery disease (CAD). In this protocol, we compared patients with normal LV function to those with LV dysfunction and CHF. In patients with cardiomyopathy, myocardial blood flow at rest was normal but flow reserve (after dipyridamole infusion) was significantly impaired (1.7 +/- 0.08) compared with normal subjects (2.7 +/- 0.01; p

AB - There is convincing evidence that (prolonged) episodes of myocardial ischemia lead to impairment of left ventricular (LV) function and ultimately to chronic congestive hear? failure (CHF), but whether the opposite is also true has not been well established. We studied this issue in two groups of CHF patients with positron emission tomography (PET)by using [N-13]ammonia ((NH3)-N-13) as a tracer. In the first protocol we compared 12 patients with idiopathic dilated cardiomyopathy (who have normal coronary arteries) with 12 healthy controls, In the second protocol we studied a group of 24 patients with documented coronary artery disease (CAD). In this protocol, we compared patients with normal LV function to those with LV dysfunction and CHF. In patients with cardiomyopathy, myocardial blood flow at rest was normal but flow reserve (after dipyridamole infusion) was significantly impaired (1.7 +/- 0.08) compared with normal subjects (2.7 +/- 0.01; p

KW - congestive heart failure

KW - idiopathic dilated cardiomyopathy

KW - ischemia

KW - left ventricular function

KW - metabolic studies

KW - MYOCARDIAL BLOOD-FLOW

KW - CHRONIC HEART-FAILURE

KW - WALL-MOTION

KW - METABOLISM

KW - CARVEDILOL

KW - TOMOGRAPHY

KW - PERFUSION

KW - ANGINA

M3 - Article

VL - 32

SP - S46-S51

JO - Journal of Cardiovascular Pharmacology

JF - Journal of Cardiovascular Pharmacology

SN - 0160-2446

ER -

ID: 3745402