Publication

Interactions between noradrenaline and corticosteroids in the brain: From electrical activity to cognitive performance

Krugers, H. J., Karst, H. & Joels, M., 9-Apr-2012, In : Frontiers in cellular neuroscience. 6, 10 p., 15.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Krugers, H. J., Karst, H., & Joels, M. (2012). Interactions between noradrenaline and corticosteroids in the brain: From electrical activity to cognitive performance. Frontiers in cellular neuroscience, 6, [15]. https://doi.org/10.3389/fncel.2012.00015

Author

Krugers, Harm J. ; Karst, Henk ; Joels, Marian. / Interactions between noradrenaline and corticosteroids in the brain : From electrical activity to cognitive performance. In: Frontiers in cellular neuroscience. 2012 ; Vol. 6.

Harvard

Krugers, HJ, Karst, H & Joels, M 2012, 'Interactions between noradrenaline and corticosteroids in the brain: From electrical activity to cognitive performance', Frontiers in cellular neuroscience, vol. 6, 15. https://doi.org/10.3389/fncel.2012.00015

Standard

Interactions between noradrenaline and corticosteroids in the brain : From electrical activity to cognitive performance. / Krugers, Harm J.; Karst, Henk; Joels, Marian.

In: Frontiers in cellular neuroscience, Vol. 6, 15, 09.04.2012.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Krugers HJ, Karst H, Joels M. Interactions between noradrenaline and corticosteroids in the brain: From electrical activity to cognitive performance. Frontiers in cellular neuroscience. 2012 Apr 9;6. 15. https://doi.org/10.3389/fncel.2012.00015


BibTeX

@article{3c10c99bd38b47da8a0bbd727be8e062,
title = "Interactions between noradrenaline and corticosteroids in the brain: From electrical activity to cognitive performance",
abstract = "One of the core reactions in response to a stressful situation is the activation of the hypothalamus -pituitary-adrenal axis which increases the release of glucocorticoid hormones from the adrenal glands. In concert with other neuro-modulators, such as (nor)adrenaline, these hormones enable and promote cognitive adaptation to stressful events. Recent studies have demonstrated that glucocorticoid hormones and noradrenaline, via their receptors, can both rapidly and persistently regulate the function of excitatory synapses which are critical for storage of information. Here we will review how glucocorticoids and noradrenaline alone and in synergy dynamically tune these synapses in the hippocampus and amygdala, and discuss how these hormones interact to promote behavioral adaptation to stressful situations.",
keywords = "hippocampus, amygdala, mouse, electrophysiology, glutamate, AMPA-RECEPTOR TRAFFICKING, LONG-TERM POTENTIATION, STRESS HORMONE CORTICOSTERONE, BETA-ADRENERGIC MODULATION, POST-TRAINING INJECTIONS, HIPPOCAMPAL CA1 REGION, BASOLATERAL AMYGDALA, SYNAPTIC PLASTICITY, EMOTIONAL MEMORY, GLUCOCORTICOID-RECEPTORS",
author = "Krugers, {Harm J.} and Henk Karst and Marian Joels",
year = "2012",
month = "4",
day = "9",
doi = "10.3389/fncel.2012.00015",
language = "English",
volume = "6",
journal = "Frontiers in cellular neuroscience",
issn = "1662-5102",
publisher = "Frontiers Media SA",

}

RIS

TY - JOUR

T1 - Interactions between noradrenaline and corticosteroids in the brain

T2 - From electrical activity to cognitive performance

AU - Krugers, Harm J.

AU - Karst, Henk

AU - Joels, Marian

PY - 2012/4/9

Y1 - 2012/4/9

N2 - One of the core reactions in response to a stressful situation is the activation of the hypothalamus -pituitary-adrenal axis which increases the release of glucocorticoid hormones from the adrenal glands. In concert with other neuro-modulators, such as (nor)adrenaline, these hormones enable and promote cognitive adaptation to stressful events. Recent studies have demonstrated that glucocorticoid hormones and noradrenaline, via their receptors, can both rapidly and persistently regulate the function of excitatory synapses which are critical for storage of information. Here we will review how glucocorticoids and noradrenaline alone and in synergy dynamically tune these synapses in the hippocampus and amygdala, and discuss how these hormones interact to promote behavioral adaptation to stressful situations.

AB - One of the core reactions in response to a stressful situation is the activation of the hypothalamus -pituitary-adrenal axis which increases the release of glucocorticoid hormones from the adrenal glands. In concert with other neuro-modulators, such as (nor)adrenaline, these hormones enable and promote cognitive adaptation to stressful events. Recent studies have demonstrated that glucocorticoid hormones and noradrenaline, via their receptors, can both rapidly and persistently regulate the function of excitatory synapses which are critical for storage of information. Here we will review how glucocorticoids and noradrenaline alone and in synergy dynamically tune these synapses in the hippocampus and amygdala, and discuss how these hormones interact to promote behavioral adaptation to stressful situations.

KW - hippocampus

KW - amygdala

KW - mouse

KW - electrophysiology

KW - glutamate

KW - AMPA-RECEPTOR TRAFFICKING

KW - LONG-TERM POTENTIATION

KW - STRESS HORMONE CORTICOSTERONE

KW - BETA-ADRENERGIC MODULATION

KW - POST-TRAINING INJECTIONS

KW - HIPPOCAMPAL CA1 REGION

KW - BASOLATERAL AMYGDALA

KW - SYNAPTIC PLASTICITY

KW - EMOTIONAL MEMORY

KW - GLUCOCORTICOID-RECEPTORS

U2 - 10.3389/fncel.2012.00015

DO - 10.3389/fncel.2012.00015

M3 - Review article

VL - 6

JO - Frontiers in cellular neuroscience

JF - Frontiers in cellular neuroscience

SN - 1662-5102

M1 - 15

ER -

ID: 65869134