Publication

Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions: A Comparative In Vitro Study

Pragt, H., van Melle, J. P., Mariani, M. A., Verkerke, G. J. & Ebels, T., Mar-2019, In : World journal for pediatric and congenital heart surgery. 10, 2, p. 145-150 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

APA

Pragt, H., van Melle, J. P., Mariani, M. A., Verkerke, G. J., & Ebels, T. (2019). Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions: A Comparative In Vitro Study. World journal for pediatric and congenital heart surgery, 10(2), 145-150. https://doi.org/10.1177/2150135118818760

Author

Pragt, Hanna ; van Melle, Joost P ; Mariani, Massimo A ; Verkerke, Gijsbertus J ; Ebels, Tjark. / Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions : A Comparative In Vitro Study. In: World journal for pediatric and congenital heart surgery. 2019 ; Vol. 10, No. 2. pp. 145-150.

Harvard

Pragt, H, van Melle, JP, Mariani, MA, Verkerke, GJ & Ebels, T 2019, 'Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions: A Comparative In Vitro Study', World journal for pediatric and congenital heart surgery, vol. 10, no. 2, pp. 145-150. https://doi.org/10.1177/2150135118818760

Standard

Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions : A Comparative In Vitro Study. / Pragt, Hanna; van Melle, Joost P; Mariani, Massimo A; Verkerke, Gijsbertus J; Ebels, Tjark.

In: World journal for pediatric and congenital heart surgery, Vol. 10, No. 2, 03.2019, p. 145-150.

Research output: Contribution to journalArticleAcademicpeer-review

Vancouver

Pragt H, van Melle JP, Mariani MA, Verkerke GJ, Ebels T. Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions: A Comparative In Vitro Study. World journal for pediatric and congenital heart surgery. 2019 Mar;10(2):145-150. https://doi.org/10.1177/2150135118818760


BibTeX

@article{1140d6cc3a1347d6a385da6737e1f60b,
title = "Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions: A Comparative In Vitro Study",
abstract = "OBJECTIVE: Hinge washing is a crucial factor in the prevention of mechanical prosthetic valvar thrombosis, especially in the pulmonary valve position. The aim of this laboratory study was to determine the relationship between pressure difference and the amount of hinge washing in the closed position, using the pressures that are normal for the right ventricle and pulmonary artery.METHODS: In an in vitro setting, four different bileaflet mechanical valves were tested for hinge washing in closed position. Based on similarity in inner diameter (range: 20.5-21.4 mm), the following valves were tested: Abbott SJM Regent size 23, Cryolife On-X size 23, LivaNova Carbomedics-R size 25, Medtronic Open Pivot (M-OP)-A size 25. Tests were carried out in a range between 3 and 100 mm Hg pressure difference, using water as a test fluid. The amount of leakage per minute through the closed valve was measured.RESULTS: All four valves showed an increase in leakage with increasing transvalvar gradient, and the relationship between pressure and leakage behaves in logarithmic fashion. Leakage under normal pulmonary diastolic pressure conditions (10 mm Hg) was between 23.3{\%} and 29.3{\%} of the leakage under aortic diastolic pressure conditions (80 mm Hg). The Cryolife On-X valve showed the highest closed leakage volume under pulmonary conditions (10 mm Hg) 0.254 ± 0.01 (L/min), where the Medtronic M-OP showed the lowest leakage volume with 0.125 ± 0.014 (mL/min).CONCLUSION: Hinge washing is related to transvalvar pressure difference in closed position. Valve brands differed significantly from each other in the amount of hinge washing.",
author = "Hanna Pragt and {van Melle}, {Joost P} and Mariani, {Massimo A} and Verkerke, {Gijsbertus J} and Tjark Ebels",
year = "2019",
month = "3",
doi = "10.1177/2150135118818760",
language = "English",
volume = "10",
pages = "145--150",
journal = "World journal for pediatric and congenital heart surgery",
issn = "2150-1351",
publisher = "SAGE Publications Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Influence of Transvalvar Pressure Gradient on Hinge Washing in Closed Mechanical Prosthetic Cardiac Valves Under Pulmonary Pressure Conditions

T2 - A Comparative In Vitro Study

AU - Pragt, Hanna

AU - van Melle, Joost P

AU - Mariani, Massimo A

AU - Verkerke, Gijsbertus J

AU - Ebels, Tjark

PY - 2019/3

Y1 - 2019/3

N2 - OBJECTIVE: Hinge washing is a crucial factor in the prevention of mechanical prosthetic valvar thrombosis, especially in the pulmonary valve position. The aim of this laboratory study was to determine the relationship between pressure difference and the amount of hinge washing in the closed position, using the pressures that are normal for the right ventricle and pulmonary artery.METHODS: In an in vitro setting, four different bileaflet mechanical valves were tested for hinge washing in closed position. Based on similarity in inner diameter (range: 20.5-21.4 mm), the following valves were tested: Abbott SJM Regent size 23, Cryolife On-X size 23, LivaNova Carbomedics-R size 25, Medtronic Open Pivot (M-OP)-A size 25. Tests were carried out in a range between 3 and 100 mm Hg pressure difference, using water as a test fluid. The amount of leakage per minute through the closed valve was measured.RESULTS: All four valves showed an increase in leakage with increasing transvalvar gradient, and the relationship between pressure and leakage behaves in logarithmic fashion. Leakage under normal pulmonary diastolic pressure conditions (10 mm Hg) was between 23.3% and 29.3% of the leakage under aortic diastolic pressure conditions (80 mm Hg). The Cryolife On-X valve showed the highest closed leakage volume under pulmonary conditions (10 mm Hg) 0.254 ± 0.01 (L/min), where the Medtronic M-OP showed the lowest leakage volume with 0.125 ± 0.014 (mL/min).CONCLUSION: Hinge washing is related to transvalvar pressure difference in closed position. Valve brands differed significantly from each other in the amount of hinge washing.

AB - OBJECTIVE: Hinge washing is a crucial factor in the prevention of mechanical prosthetic valvar thrombosis, especially in the pulmonary valve position. The aim of this laboratory study was to determine the relationship between pressure difference and the amount of hinge washing in the closed position, using the pressures that are normal for the right ventricle and pulmonary artery.METHODS: In an in vitro setting, four different bileaflet mechanical valves were tested for hinge washing in closed position. Based on similarity in inner diameter (range: 20.5-21.4 mm), the following valves were tested: Abbott SJM Regent size 23, Cryolife On-X size 23, LivaNova Carbomedics-R size 25, Medtronic Open Pivot (M-OP)-A size 25. Tests were carried out in a range between 3 and 100 mm Hg pressure difference, using water as a test fluid. The amount of leakage per minute through the closed valve was measured.RESULTS: All four valves showed an increase in leakage with increasing transvalvar gradient, and the relationship between pressure and leakage behaves in logarithmic fashion. Leakage under normal pulmonary diastolic pressure conditions (10 mm Hg) was between 23.3% and 29.3% of the leakage under aortic diastolic pressure conditions (80 mm Hg). The Cryolife On-X valve showed the highest closed leakage volume under pulmonary conditions (10 mm Hg) 0.254 ± 0.01 (L/min), where the Medtronic M-OP showed the lowest leakage volume with 0.125 ± 0.014 (mL/min).CONCLUSION: Hinge washing is related to transvalvar pressure difference in closed position. Valve brands differed significantly from each other in the amount of hinge washing.

U2 - 10.1177/2150135118818760

DO - 10.1177/2150135118818760

M3 - Article

VL - 10

SP - 145

EP - 150

JO - World journal for pediatric and congenital heart surgery

JF - World journal for pediatric and congenital heart surgery

SN - 2150-1351

IS - 2

ER -

ID: 82674431