Publication

INFLUENCE OF AMBIENT PLASMA NORADRENALINE ON RENAL HEMODYNAMICS IN TYPE-1 (INSULIN-DEPENDENT) DIABETIC-PATIENTS AND HEALTHY-SUBJECTS

HOOGENBERG, K., GIRBES, ARJ., STEGEMAN, CA., SLUITER, WJ., REITSMA, WD. & DULLAART, RPF., Feb-1995, In : Scandinavian Journal of Clinical & Laboratory Investigation. 55, 1, p. 15-22 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Imbalances in renal vasodilatory and vasoconstrictive mechanisms are responsible for the renal haemodynamic changes observed in Type 1 diabetes mellitus. Animal experiments have shown that noradrenaline (NA) infusion increases the intraglomerular pressure by predominantly efferent arteriolar vasoconstriction. The relationships between ambient plasma NA levels and renal haemodynamics were studied in 18 healthy control subjects (group C); in 17 normoalbuminuric diabetic patients (group D1) (albumin excretion rate (Ualb V)

Original languageEnglish
Pages (from-to)15-22
Number of pages8
JournalScandinavian Journal of Clinical & Laboratory Investigation
Volume55
Issue number1
Publication statusPublished - Feb-1995

    Keywords

  • EFFECTIVE RENAL PLASMA FLOW, GLOMERULAR FILTRATION RATE, PLASMA NORADRENALINE, TYPE 1 DIABETES MELLITUS, GLOMERULAR-FILTRATION RATE, IDDM PATIENTS, NEPHROPATHY, MELLITUS, MICROALBUMINURIA, HYPERFILTRATION, NOREPINEPHRINE, ALBUMINURIA, ANGIOTENSIN, PRESSURE

ID: 6414743