Publication

Infection and inflammatory mechanisms

Van Dyke, T. E. & van Winkelhoff, A. J., Apr-2013, In : Journal of Clinical Periodontology. 40, p. S1-S7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

  • Thomas E. Van Dyke
  • Arie Jan van Winkelhoff

This introductory article examines the potential mechanisms that may play a role in the associations between periodontitis and the systemic conditions being considered in the EFP/AAP Workshop in Segovia, Spain. Three basic mechanisms have been postulated to play a role in these interactions; metastatic infections, inflammation and inflammatory injury, and adaptive immunity. The potential role of each alone and together is considered in in vitro and animal studies and in human studies when available. This is not a systematic or critical review, but rather an overview of the field to set the stage for the critical reviews in each of the working groups.

Original languageEnglish
Pages (from-to)S1-S7
Number of pages7
JournalJournal of Clinical Periodontology
Volume40
Publication statusPublished - Apr-2013

    Keywords

  • cardiovascular disease, infection, inflammation, pathogenesis, periodontitis, systemic diseases, HUMAN PERIODONTAL-LIGAMENT, CORONARY-HEART-DISEASE, TUMOR-NECROSIS-FACTOR, REGULATORY T-CELLS, ATHEROSCLEROTIC CARDIOVASCULAR-DISEASE, ANTIINFLAMMATORY LIPID MEDIATORS, EDITORS CONSENSUS PERIODONTITIS, JOURNAL-OF-CARDIOLOGY, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS, PORPHYROMONAS-GINGIVALIS

ID: 5856839