Publication

In vivo approaches to investigate ANCA-associated vasculitis: lessons and limitations

Heeringa, P. & Little, M. A., 28-Feb-2011, In : Arthritis Research and Therapy. 13, 1, 10 p., 204.

Research output: Contribution to journalReview articleAcademicpeer-review

APA

Heeringa, P., & Little, M. A. (2011). In vivo approaches to investigate ANCA-associated vasculitis: lessons and limitations. Arthritis Research and Therapy, 13(1), [204]. https://doi.org/10.1186/ar3236

Author

Heeringa, Peter ; Little, Mark A. / In vivo approaches to investigate ANCA-associated vasculitis : lessons and limitations. In: Arthritis Research and Therapy. 2011 ; Vol. 13, No. 1.

Harvard

Heeringa, P & Little, MA 2011, 'In vivo approaches to investigate ANCA-associated vasculitis: lessons and limitations', Arthritis Research and Therapy, vol. 13, no. 1, 204. https://doi.org/10.1186/ar3236

Standard

In vivo approaches to investigate ANCA-associated vasculitis : lessons and limitations. / Heeringa, Peter; Little, Mark A.

In: Arthritis Research and Therapy, Vol. 13, No. 1, 204, 28.02.2011.

Research output: Contribution to journalReview articleAcademicpeer-review

Vancouver

Heeringa P, Little MA. In vivo approaches to investigate ANCA-associated vasculitis: lessons and limitations. Arthritis Research and Therapy. 2011 Feb 28;13(1). 204. https://doi.org/10.1186/ar3236


BibTeX

@article{adb0ddc6a7274c26af322dc9ef311b49,
title = "In vivo approaches to investigate ANCA-associated vasculitis: lessons and limitations",
abstract = "Anti-neutrophil cytoplasm autoantibody (ANCA)-associated diseases are autoimmune conditions characterized by necrotizing inflammation of small blood vessels. The immunogenesis and etiology of these conditions are unknown, but our knowledge of the immunopathogenesis has increased considerably in recent years. In this review, we discuss the animal models currently used to investigate the mechanisms of vascular injury and to test novel therapies. We outline their advantages and limitations and propose potential directions for future research.",
keywords = "ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES, ANTIBODY-MEDIATED GLOMERULONEPHRITIS, IGG GLYCAN HYDROLYSIS, FC-GAMMA RECEPTORS, CRESCENTIC GLOMERULONEPHRITIS, ANTIMYELOPEROXIDASE ANTIBODIES, SYSTEMIC VASCULITIS, NECROTIZING GLOMERULONEPHRITIS, WEGENER AUTOANTIGEN, MERCURIC-CHLORIDE",
author = "Peter Heeringa and Little, {Mark A.}",
year = "2011",
month = "2",
day = "28",
doi = "10.1186/ar3236",
language = "English",
volume = "13",
journal = "Arthritis Research and Therapy",
issn = "1478-6362",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - In vivo approaches to investigate ANCA-associated vasculitis

T2 - lessons and limitations

AU - Heeringa, Peter

AU - Little, Mark A.

PY - 2011/2/28

Y1 - 2011/2/28

N2 - Anti-neutrophil cytoplasm autoantibody (ANCA)-associated diseases are autoimmune conditions characterized by necrotizing inflammation of small blood vessels. The immunogenesis and etiology of these conditions are unknown, but our knowledge of the immunopathogenesis has increased considerably in recent years. In this review, we discuss the animal models currently used to investigate the mechanisms of vascular injury and to test novel therapies. We outline their advantages and limitations and propose potential directions for future research.

AB - Anti-neutrophil cytoplasm autoantibody (ANCA)-associated diseases are autoimmune conditions characterized by necrotizing inflammation of small blood vessels. The immunogenesis and etiology of these conditions are unknown, but our knowledge of the immunopathogenesis has increased considerably in recent years. In this review, we discuss the animal models currently used to investigate the mechanisms of vascular injury and to test novel therapies. We outline their advantages and limitations and propose potential directions for future research.

KW - ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES

KW - ANTIBODY-MEDIATED GLOMERULONEPHRITIS

KW - IGG GLYCAN HYDROLYSIS

KW - FC-GAMMA RECEPTORS

KW - CRESCENTIC GLOMERULONEPHRITIS

KW - ANTIMYELOPEROXIDASE ANTIBODIES

KW - SYSTEMIC VASCULITIS

KW - NECROTIZING GLOMERULONEPHRITIS

KW - WEGENER AUTOANTIGEN

KW - MERCURIC-CHLORIDE

U2 - 10.1186/ar3236

DO - 10.1186/ar3236

M3 - Review article

VL - 13

JO - Arthritis Research and Therapy

JF - Arthritis Research and Therapy

SN - 1478-6362

IS - 1

M1 - 204

ER -

ID: 5314225