Improvement of Sodium Status to Optimize the Efficacy of Renin-Angiotensin System Blockade

Laverman, G. D. & Navis, G., Dec-2011, In : Current Hypertension Reports. 13, 6, p. 397-399 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Blockade of the renin-angiotensin-aldosterone system (RAAS) offers superior renoprotection in the treatment of patients with hypertension, but the efficacy of RAAS inhibition strongly depends on sodium status, presumably in relation to extracellular volume status. Because assessing volume status by physical examination is challenging, 24-hour urine collection and NT-proBNP levels are useful tools for guiding volume management and achieving sodium status targets.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalCurrent Hypertension Reports
Issue number6
Publication statusPublished - Dec-2011


  • Hypertension, Chronic kidney disease, Blood pressure, Therapy, Renoprotection, Sodium, Renin-angiotensin system, Renin-angiotensin-aldosterone system, RAAS blockade, N-terminal pro-brain natriuretic peptide, NT-proBNP, 24-hour urine collection, Extracellular volume

ID: 5480061